Gundmi Shubha, Maiya Arun G, Bhat Anil K, Hande Manjunatha H, Kumar A Sampath
Department of Physiotherapy, School of Allied Health Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576 104, India.
Department of Orthopaedics, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, 576 104, India.
Diabetes Metab Syndr. 2019 Mar-Apr;13(2):981-984. doi: 10.1016/j.dsx.2019.01.003. Epub 2019 Jan 16.
In people with type 2 diabetes mellitus, there is an increase in basal metabolic rate (BMR) which is associated with level of glycaemic control. Women with postmenopausal osteoporosis have decreased BMR. The aim of the present study is to find the BMR using Meffin-St Jeor predictive equation in women with type 2 diabetes mellitus (T2DM) who have attained menopause with osteoporosis.
MATERIALS & METHODS: 100 women who have attained menopause, who were diagnosed to have osteoporosis with type 2 diabetes mellitus were assessed for BMR using Meffin-St Jeor predictive equation. Detailed history of diabetes and menopause were obtained. Blood glucose value was measured using standard glucometers. Body composition for visceral fat (VF) was measured using bioelectrical impedance analysis. Level of physical activity of the participants was measured using global physical activity questionnaire (GPAQ).
The median BMR of the participants was 1.075 (714, 1483.25). Statistically significant correlation was found between BMR and GPAQ (r = 0.731), BMR and VF (r = 0.678). However BMR was not correlated with FBS (r = 0.083) duration of diabetes (r = -0.046).
There is a decrease in BMR in women with T2DM with postmenopausal osteoporosis. BMR was significantly correlated with level of physical activity and visceral fat.
在2型糖尿病患者中，基础代谢率（BMR）升高，且与血糖控制水平相关。绝经后骨质疏松症女性的基础代谢率降低。本研究的目的是使用Miffin-St Jeor预测方程，在已绝经且患有骨质疏松症的2型糖尿病（T2DM）女性中测定基础代谢率。
对100名已绝经、被诊断为患有2型糖尿病骨质疏松症的女性，使用Miffin-St Jeor预测方程评估基础代谢率。获取详细的糖尿病和绝经病史。使用标准血糖仪测量血糖值。使用生物电阻抗分析法测量内脏脂肪（VF）的身体成分。使用全球体力活动问卷（GPAQ）测量参与者的体力活动水平。
参与者的基础代谢率中位数为1.075（714，1483.25）。基础代谢率与GPAQ（r = 0.731）、基础代谢率与VF（r = 0.678）之间存在统计学显著相关性。然而，基础代谢率与空腹血糖（r = 0.083）、糖尿病病程（r = -0.046）无关。
患有绝经后骨质疏松症的2型糖尿病女性基础代谢率降低。基础代谢率与体力活动水平和内脏脂肪显著相关。
