Gordon D, MacCuish A C
Diabetic Unit, Glasgow Royal Infirmary.
Scott Med J. 1988 Feb;33(1):212-3. doi: 10.1177/003693308803300111.
Modern management of diabetic ketoacidosis has reduced mortality of this condition from inevitable death in the pre-insulin era to less than 5% in specialised centres. Most fatalities now reflect the underlying disease which has caused metabolic decompensation, such as acute myocardial infarction, cerebrovascular accident or septicaemia. However patients may still die as a direct result of the metabolic disturbances per se and the rare complication of cerebral oedema in diabetic ketoacidosis is almost invariably associated with fatal outcome.
糖尿病酮症酸中毒的现代治疗已将该病症的死亡率从前胰岛素时代的不可避免死亡降低至专业中心的5%以下。现在，大多数死亡反映的是导致代谢失代偿的基础疾病，如急性心肌梗死、脑血管意外或败血症。然而，患者仍可能直接死于代谢紊乱本身，糖尿病酮症酸中毒中罕见的脑水肿并发症几乎总是与致命结局相关。
