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成功应用姑息性肽受体放射性核素治疗神经内分泌肿瘤不可切除肝转移导致的即将发生的腔静脉压迫。

Successful palliative peptide receptor radionuclide therapy for impending compression of vena cava due to unresectable liver metastasis of neuroendocrine tumor.

作者信息

Ataeinia Bahar, Loberg Christina, Kravets Hanna, Beheshti Mohsen, von Mallek Dirk, Mottaghy Felix M, Heinzel Alexander

机构信息

Department of Nuclear Medicine, University Hospital RWTH Aachen, Aachen, Germany.

Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

EXCLI J. 2019 May 21;18:273-276. doi: 10.17179/excli2019-1220. eCollection 2019.

DOI:10.17179/excli2019-1220
PMID:31338000
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635723/
Abstract

We present the case of a 77 year old male patient with metastatic pancreatic neuroendocrine tumor (NET). The patient was initially treated by extensive surgical resection that however, led to severe complications with delayed recovery. During follow-up, a number of new liver metastases were detected, one of which was in segment I with impending compression of the inferior vena cava. Due to age and general condition of the patient, instead of further surgical treatment, the patient received four cycles of Lu-DOTATOC resulting in an overall partial response with successful tumor reduction in liver segment I, resolving an impending compression of vena cava.

摘要

我们报告一例77岁男性转移性胰腺神经内分泌肿瘤(NET)患者的病例。该患者最初接受了广泛的手术切除,但术后出现严重并发症,恢复延迟。在随访期间,发现了多处新的肝转移灶,其中一个位于Ⅰ段,即将压迫下腔静脉。鉴于患者的年龄和一般状况,患者未接受进一步的手术治疗,而是接受了四个周期的镥-奥曲肽治疗,总体上部分缓解,成功缩小了肝Ⅰ段的肿瘤,解除了即将发生的腔静脉压迫。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d758/6635723/7624fd6ac845/EXCLI-18-273-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d758/6635723/ff976c003ae3/EXCLI-18-273-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d758/6635723/7624fd6ac845/EXCLI-18-273-g-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d758/6635723/ff976c003ae3/EXCLI-18-273-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d758/6635723/7624fd6ac845/EXCLI-18-273-g-002.jpg

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