饮茶与骨折风险：一项更新的荟萃分析。
Tea consumption and risk of fractures: an updated meta-analysis.
机构信息
Department of Epidemiology and Health Statistics, The School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, Shandong, People's Republic of China.
出版信息
Osteoporos Int. 2019 Oct;30(10):1941-1951. doi: 10.1007/s00198-019-05095-3. Epub 2019 Jul 23.
UNLABELLED
This meta-analysis included 16 studies, involving seven cohort studies and nine case-control studies, and the results indicated that tea consumption may be associated with a reduced the risk of fractures.
INTRODUCTION
Regarding relationship of tea consumption with the risk of fractures remains controversial. We performed a meta-analysis to elucidate the association between tea consumption and the risk of fractures.
METHODS
Relevant articles were identified up to March 2019 by searching PubMed, Web of Science, and Embase databases. The pooled relative risks (RRs) with 95% confidence intervals (CIs) were computed utilizing fixed or random effects model based on heterogeneity.
RESULTS
Altogether 16 studies (seven cohort and nine case-control studies) were included in this meta-analysis, involving 772,707 participants with 37,166 fracture cases. The RRs (95% CIs) of fracture for the highest versus lowest category of tea consumption were 0.86 (0.78-0.94). Subgroup analysis indicated significant associations in cohort studies (0.90 (0.86-0.94)) and case-control studies (0.77 (0.69-0.85)).
CONCLUSIONS
The current meta-analysis indicates that tea consumption may be associated with a reduced the risk of fractures.
未标注
本荟萃分析纳入了 16 项研究，包括 7 项队列研究和 9 项病例对照研究，结果表明，饮茶可能与骨折风险降低有关。
简介
关于饮茶与骨折风险的关系仍存在争议。我们进行了荟萃分析，以阐明饮茶与骨折风险之间的关系。
方法
截至 2019 年 3 月，通过检索 PubMed、Web of Science 和 Embase 数据库，确定了相关文章。根据异质性，使用固定或随机效应模型计算合并的相对风险（RR）和 95%置信区间（CI）。
结果
共有 16 项研究（7 项队列研究和 9 项病例对照研究）纳入本荟萃分析，共涉及 772707 名参与者和 37166 例骨折病例。饮茶量最高与最低组的 RR（95%CI）为 0.86（0.78-0.94）。亚组分析表明，在队列研究（0.90（0.86-0.94））和病例对照研究（0.77（0.69-0.85））中存在显著相关性。
结论
目前的荟萃分析表明，饮茶可能与骨折风险降低有关。
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