Department of Physical Medicine and Rehabilitation, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
Department of Physical Medicine and Rehabilitation, Yuksekova State Hospital, Hakkari, Turkey.
Rheumatol Int. 2020 Jan;40(1):75-80. doi: 10.1007/s00296-019-04361-1. Epub 2019 Jul 23.
The objective for this study is to evaluate the femoral cartilage thickness in patients with/without uveitis in Behçet's disease (BD). Patients with BD aged 18-70 years were included. The demographic and clinical characteristics of the patients were recorded. The thickness of femoral articular cartilage was measured with musculoskeletal ultrasound. Cartilage thickness was measured bilaterally from the central points of medial condyle (MFC), lateral condyle (LFC), and intercondylar area (ICA). 20 patients with uveitis [uveitis (+)] and 20 patients without uveitis [uveitis (-)] were included. Both right and left MFC and LFC had statistically significant thinner cartilage in uveitis (+) group (p < 0.05). For the ICA, uveitis (+) patients had thinner femoral cartilage than uveitis (-) patients; however, in the left side, statistically significance could not be detected. Femoral cartilage was thinner in uveitis (+) patients than in uveitis (-) patients in BD. This relationship between uveitis and femoral cartilage thickness may be helpful in the prevention and early treatment of cartilage degeneration.
本研究旨在评估 Behçet 病（BD）患者中伴或不伴葡萄膜炎的股骨软骨厚度。纳入年龄在 18-70 岁之间的 BD 患者。记录患者的人口统计学和临床特征。使用肌肉骨骼超声测量股骨关节软骨的厚度。从内侧髁（MFC）、外侧髁（LFC）和髁间区（ICA）的中心点双侧测量软骨厚度。纳入 20 例伴葡萄膜炎（葡萄膜炎（+））和 20 例不伴葡萄膜炎（葡萄膜炎（-））患者。葡萄膜炎（+）组双侧 MFC 和 LFC 的软骨均明显变薄（p<0.05）。对于 ICA，葡萄膜炎（+）患者的股骨软骨比葡萄膜炎（-）患者薄；然而，在左侧，未检测到统计学意义。BD 患者中，葡萄膜炎（+）患者的股骨软骨比葡萄膜炎（-）患者薄。葡萄膜炎与股骨软骨厚度之间的这种关系可能有助于预防和早期治疗软骨退化。
