Kitamura M, Namiki M, Okuyama A, Arita N, Mizutani S, Sonoda T
Department of Urology and Neurosurgery, Osaka University Hospital, Japan.
Urol Int. 1988;43(2):122-4. doi: 10.1159/000281320.
A 21-year-old man, who had had normal sexuality beforehand, noticed a decrease in libido and potency, as well as loss of ejaculation. Endocrine evaluation showed normal serum levels of gonadotropins but a low testosterone level. The response to clomiphene citrate was poor while those to luteinizing hormone-releasing hormone and human chorionic gonadotropin were within normal limits. A tumor found in the septum pellucidum through brain-computerized tomography was resected. Histologically it proved to be a mixed tumor composed of astrocytoma and oligodendroglioma. Three months after the operation the patient had recovered normal sexual functions and endocrine evaluations, including the responsiveness to clomiphene citrate, had been restored. This case suggests the existence of some stimulatory fiber for the secretion of luteinizing hormone in the septum pellucidum.
一名21岁男性，此前性功能正常，却出现性欲和勃起功能减退，以及射精障碍。内分泌评估显示促性腺激素血清水平正常，但睾酮水平较低。对枸橼酸氯米芬的反应不佳，而对促黄体生成素释放激素和人绒毛膜促性腺激素的反应在正常范围内。通过脑部计算机断层扫描在透明隔发现一个肿瘤并进行了切除。组织学检查证明是一个由星形细胞瘤和少突胶质细胞瘤组成的混合性肿瘤。术后三个月，患者性功能恢复正常，内分泌评估包括对枸橼酸氯米芬的反应也已恢复。该病例提示透明隔中存在一些刺激促黄体生成素分泌的纤维。
