Kitamura M, Nakamura M, Namiki M, Okuyama A, Sonoda T, Arita N, Mizutani S
Department of Urology, Osaka University Medical School.
Hinyokika Kiyo. 1988 Dec;34(12):2193-5.
A 21-year-old man, who had had normal sexuality, noticed a decrease in libido and potency as well as loss of ejaculation. Endocrinological evaluation showed normal serum levels of gonadotropins but a low testosterone level. The response to clomiphene citrate was poor while the response to luteinizing hormone-releasing hormone and human chorionic gonadotropin were within normal limits. By the examination of brain computerized tomography a tumor was detected in the septum pellucidum and was resected. Histologically it proved to be a mixed tumor composed of astrocytoma and oligodendroglioma. Two months after the operation the patient had recovered normal sexual functions and the endocrinological functions, including the responsiveness to clomiphene citrate, had been restored. This case suggests the existence of some stimulatory fiber for the secretion of luteinizing hormone in the septum pellucidum.
一名21岁男性，其性功能原本正常，却出现性欲和勃起功能减退以及射精障碍。内分泌检查显示促性腺激素血清水平正常，但睾酮水平较低。该患者对枸橼酸氯米芬反应不佳，而对促黄体生成素释放激素和人绒毛膜促性腺激素的反应在正常范围内。通过脑部计算机断层扫描检查，在透明隔发现一个肿瘤并将其切除。组织学检查证明这是一个由星形细胞瘤和少突胶质细胞瘤组成的混合性肿瘤。术后两个月，患者性功能恢复正常，内分泌功能也得以恢复，包括对枸橼酸氯米芬的反应性。该病例提示透明隔存在一些刺激促黄体生成素分泌的纤维。
