矿物离子负载珠（DC 珠）在双能 CT 低 keV 单色图像和 T1 加权梯度回波 MRI 上的不透明度。
The opacity of mineral ion-loaded bead (DC beads) on low-keV monochromatic images from dual energy CT and T1-weighted gradient-echo MRI.
机构信息
Department of Diagnostic Radiology, Hiroshima Prefectural Hospital, Minami-ku, Ujinakanda, 1-5-54, Hiroshima, 734-8530, Japan.
Department of Radiology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
出版信息
Jpn J Radiol. 2019 Sep;37(9):660-665. doi: 10.1007/s11604-019-00856-w. Epub 2019 Jul 23.
PURPOSE
To evaluate the opacity of DC beads (DCB) loaded with mineral ions on low-keV monochromatic images from dual energy computed tomography (DECT) and T1-weighted gradient-echo (T1-GRE) MRI.
MATERIALS AND METHODS
Fe or Ca-loaded DCBs were prepared by mixing DCBs in 100 mM FeSO or CaSO solution and scanned by DECT from 10 min to 27 h after mixing. The Hounsfield units (HUs) of sedimented DCBs on 40-keV monochromatic images were measured. Next, we mixed DCBs in 100, 10, 5 and 1 mM FeSO solutions, and scanned these solutions from 15 to 120 min after mixing using a 3 T MR scanner. The signal-noise ratios (SNRs) of sedimented DCBs on T1-GRE were measured. Venous blood was scanned to compare with DCBs.
RESULTS
The CT values of DCBs in FeSO and CaCl solutions gradually increased, and were 113.3 and 43.1 HU at 27 h, respectively; that of blood was 17.8 HU. The SNR of DCB in 1 mM FeSO solution increased and achieved equilibrium at 120 min, and was 120.5 and higher than in the other FeSO solutions. The SNR of blood was 49.7.
CONCLUSION
Optimally Fe-loaded DCBs can be discriminated from venous blood on 40-keV monochromatic images from DECT and T1-GRE.
目的
评估双能 CT (DECT) 低千伏单色图像和 T1 加权梯度回波 (T1-GRE) MRI 中负载矿物质离子的 DC 珠 (DCB) 的不透明度。
材料和方法
通过将 DCB 混合到 100 mM FeSO 或 CaSO 溶液中，制备 Fe 或 Ca 负载的 DCB，并在混合后 10 分钟至 27 小时内通过 DECT 进行扫描。测量沉降 DCB 在 40 keV 单色图像上的 Hounsfield 单位 (HU)。接下来，我们将 DCB 混合到 100、10、5 和 1 mM FeSO 溶液中，并在混合后 15 至 120 分钟内使用 3T MR 扫描仪进行扫描。测量沉降 DCB 在 T1-GRE 上的信噪比 (SNR)。扫描静脉血以与 DCB 进行比较。
结果
FeSO 和 CaCl 溶液中 DCB 的 CT 值逐渐增加，在 27 小时时分别为 113.3 和 43.1 HU；血液的 CT 值为 17.8 HU。1 mM FeSO 溶液中 DCB 的 SNR 增加并在 120 分钟时达到平衡，为 120.5，高于其他 FeSO 溶液。血液的 SNR 为 49.7。
结论
在 DECT 和 T1-GRE 的 40 keV 单色图像上，可以区分最佳负载 Fe 的 DCB 与静脉血。
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