Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Community Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
J Gastrointest Cancer. 2020 Jun;51(2):401-411. doi: 10.1007/s12029-019-00275-0.
Colorectal cancer (CRC) is one of the most important cancers, which has various patterns in the world. The aim of this study was to determine the factor associated to survival and looking for screening in Iran.
A literature search was conducted using PubMed, Web of Science, Scopus, SID, and Magiran on June 30, 2018. Studies that performed survival analysis and the barrier of screening for colorectal cancer were included in this review.
Fifty-three articles for survival and 11 for screening were included and examined. The important factors of survival are the age, cancer stage, tumor grade, ethnicity, marital status, family history of cancer, smoking, metastasis, and obesity. For barrier of screening, the cost, shame, fear of diagnosis the cancer, absence of clinical symptoms, and time limit were determined.
Remarkably, knowledge, attitude, and behaviors about CRC screening in Iran are very moderate to poor. According to diversity of survival rates and low tendency to screening, we need to further and deepen studies of barrier and facilitators of screening.
结直肠癌（CRC）是最重要的癌症之一，在世界范围内具有多种表现形式。本研究旨在确定与伊朗生存相关的因素，并寻找筛查方法。
本研究于 2018 年 6 月 30 日使用 PubMed、Web of Science、Scopus、SID 和 Magiran 进行了文献检索。纳入了进行生存分析和结直肠癌筛查障碍研究的文献。
共纳入 53 篇关于生存的文章和 11 篇关于筛查的文章。生存的重要因素包括年龄、癌症分期、肿瘤分级、种族、婚姻状况、癌症家族史、吸烟、转移和肥胖。对于筛查障碍，确定了费用、羞耻感、对诊断癌症的恐惧、缺乏临床症状和时间限制。
值得注意的是，伊朗人对结直肠癌筛查的知识、态度和行为非常中等至较差。鉴于生存率的差异和筛查率低，我们需要进一步深入研究筛查的障碍和促进因素。
