Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Tehran West Health Center, Iran University of Medical Sciences, Tehran, Iran.
J Gastrointest Cancer. 2021 Jun;52(2):414-421. doi: 10.1007/s12029-020-00574-x. Epub 2021 Jan 4.
Colorectal cancer (CRC) is one of the most common cancers in the world. The aim of this study was to investigate its incidence and risk factors in the Iranian population.
A literature search was conducted in PubMed, Web of Science, Scopus, SID, and Magiran from inception until 2019. Studies that reported the incidence rate and risk factors of colorectal cancer were included in this review.
Twenty-one articles that reported the incidence rate and 13 that reported the risk factors were included. The incidence rate was different according to the population type, gender, age, and study year in different regions. The main risk factors for colorectal cancer were high consumption of red meat and fried food and low intake of fruits and vegetables, diabetes, a positive family history, and obesity.
The incidence of CRC has a marked variation in different parts of Iran, and various risk factors are associated with colorectal cancer. According to incidence rate and various risk factors, precise planning is needed to control colorectal cancer in the future.
结直肠癌（CRC）是世界上最常见的癌症之一。本研究旨在调查伊朗人群中 CRC 的发病率和危险因素。
从建库至 2019 年，我们在 PubMed、Web of Science、Scopus、SID 和 Magiran 中进行了文献检索。纳入了报告结直肠癌发病率和危险因素的研究。
纳入了 21 篇报告发病率的文章和 13 篇报告危险因素的文章。不同地区的人群类型、性别、年龄和研究年份不同，CRC 的发病率也不同。结直肠癌的主要危险因素是大量食用红肉和油炸食品，以及水果和蔬菜摄入不足、糖尿病、阳性家族史和肥胖。
CRC 在伊朗不同地区的发病率存在明显差异，多种危险因素与结直肠癌相关。根据发病率和各种危险因素，未来需要有针对性地规划以控制结直肠癌。
