Muñoz Cofré Rodrigo, Del Sol Mariano, Medina González Paul, Escobar Inostroza Javiera, Lizana Pablo A, Conei Daniel, Escobar Cabello Máximo
Programa de Doctorado en Ciencias Morfológicas, Universidad de La Frontera, Temuco, Chile.
Laboratorio de Función-Disfunción Ventilatoria.
Arch Argent Pediatr. 2019 Aug 1;117(4):230-236. doi: 10.5546/aap.2019.eng.230.
Obesity is associated with a rapid decrease in ventilatory function. The most common way of assessing nutritional status and measuring abdominal fat and hips are the body mass index (BMI) and the waist-hip ratio (WHR). There is scarce evidence suggesting their relation to functional residual capacity (FRC). Our objective was to determine the relation among BMI, WHR, and FRC in obese children in the city of Talca, Chile.
Male and female children were recruited (6-12 years). Weight, height, BMI, WHR, and pulmonary function were assessed; the latter with body plethysmography. Depending on data distribution, Student's t test or the Mann-Whitney U test were used for independent samples, while Pearson's or Spearman's r test was used to establish the correlation between WHR and FRC.
Children were divided into normal weight (n = 18) and obese (n = 18). A significant reduction in FRC (p = 0.025) was reported in obese children, while a reverse association was observed between WHR and FRC, which was moderate in normal weight children (s = -0.489; p = 0.03) and high in obese children (r = -0.681; p = 0.001).
Obese children showed a lower FRC compared to normal weight children, which, in turn, was associated with WHR. These results are indicative of the systemic effects caused by obesity on children's ventilatory function and the need to use body fat distribution indicators at an early age.
肥胖与通气功能迅速下降有关。评估营养状况以及测量腹部脂肪和臀部的最常用方法是体重指数（BMI）和腰臀比（WHR）。几乎没有证据表明它们与功能残气量（FRC）之间的关系。我们的目的是确定智利塔尔卡市肥胖儿童的BMI、WHR和FRC之间的关系。
招募了6至12岁的男童和女童。评估了体重、身高、BMI、WHR和肺功能；后者采用体容积描记法进行评估。根据数据分布情况，独立样本采用Student's t检验或Mann-Whitney U检验，而采用Pearson或Spearman的r检验来确定WHR与FRC之间的相关性。
儿童被分为正常体重组（n = 18）和肥胖组（n = 18）。肥胖儿童的FRC显著降低（p = 0.025），而观察到WHR与FRC呈负相关，在正常体重儿童中这种相关性为中等（s = -0.489；p = 0.03），在肥胖儿童中相关性较高（r = -0.681；p = 0.001）。
与正常体重儿童相比，肥胖儿童的FRC较低，而这又与WHR相关。这些结果表明肥胖对儿童通气功能产生的系统性影响，以及在儿童早期使用体脂分布指标的必要性。
