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[一例睾丸女性化病例]

[A case of testicular feminization].

作者信息

Araki T, Hori N, Arima K, Sugimura Y, Tochigi H, Kawamura J

机构信息

Department of Urology, School of Medicine, Mie University.

出版信息

Hinyokika Kiyo. 1988 Mar;34(3):521-3.

PMID:3133933
Abstract

A 21-year-old female visited the gynecological clinic because of primary amenorrhea. The patient was a phenotypic female with scanty pubic hair, short and blind-ending vagina and bilateral inguinal soft masses. The patients was referred to our clinic. The serum luteinizing hormone level was 27.1 mIU/ml, follicle stimulating hormone level was 8.8 mIU/ml, and testosterone level was 11 ng/ml. Chromosomal analysis of peripheral lymphocytes revealed the karyotype 46, XY. The pathological specimens of bilateral inguinal masses showed atrophic testis without spermatogenesis and with Sertoli's cell nodular hyperplasia. The diagnosis of testicular feminization was established.

摘要

一名21岁女性因原发性闭经前往妇科门诊就诊。该患者表现为女性 phenotype,阴毛稀少,阴道短且盲端,双侧腹股沟有柔软肿块。患者被转诊至我院。血清促黄体生成素水平为27.1 mIU/ml,促卵泡生成素水平为8.8 mIU/ml,睾酮水平为11 ng/ml。外周淋巴细胞染色体分析显示核型为46,XY。双侧腹股沟肿块的病理标本显示睾丸萎缩,无精子生成,伴有支持细胞结节性增生。诊断为睾丸女性化。

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