植物油的脂肪酸组成及其在伤口护理中的潜在应用。

The Fatty Acid Composition of Vegetable Oils and Their Potential Use in Wound Care.

机构信息

Anselmo Queiroz Alves, MD, is a Specialist, Maxiclínica Médica Ltda, Recife, Pernambuco, Brazil. Valdemiro Amaro da Silva, Jr, PhD, is Associate Professor, Department of Veterinary Medicine at the Federal Rural University of Pernambuco (UFRPE), Recife, Pernambuco, Brazil. At the Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil, Alexandre José da Silva Góes, PhD, is Associate Professor, Department of Antibiotics; and Mariza Severina Silva is a Master of Sciences student, Postgraduate Program in Pharmaceutical Sciences. Gibson Gomes de Oliveira, PhD, is a postdoctoral student, Research Center on Natural and Synthetic Products, Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. At the UFPE, Isla Vanessa Gomes Alves Bastos, PhD, is a postdoctoral student, Department of Antibiotics; Antonio Gomes de Castro Neto, PhD, is Substitute Professor, Department of Physiology and Pharmacology; and Antonio José Alves, PhD, is Titular Professor, Department of Pharmaceutical Sciences. Acknowledgments: The authors thank the Maxiclínica Médica Ltda and CEAN/CETENE for their contributions to research development. The authors have disclosed no financial relationships related to this article. Submitted July 26, 2018; accepted in revised form September 13, 2018; published online ahead of print May 2, 2018.

出版信息

Adv Skin Wound Care. 2019 Aug;32(8):1-8. doi: 10.1097/01.ASW.0000557832.86268.64.

DOI:10.1097/01.ASW.0000557832.86268.64

PMID:31339869

Abstract

OBJECTIVE

To evaluate the similarities among fatty acid compositions of vegetable oils sold in the Brazilian market and those present in a reference health product used to treat wounds.

METHODS

The relative amounts of fatty acids in 21 types of vegetable oils, purchased in the Brazilian market, were assessed using gas chromatography-mass spectrometry and flame ionization detection.

MAIN RESULTS

The studied oils had similar fatty acid compositions to the reference product (caprylic acid, 18.8%; capric acid, 17.4%; oleic acid, 27.5%; and linoleic acid, 28.1%). The presence of caprylic acid (10.45% ± 0.07%), capric acid (5.8% ± 0.75%), lauric acid (45.63% ± 0.93%), and myristic acid (16.33% ± 2.23%) were detected in all the vegetable oils tested. Oleic acid (52.94% ± 12.54%) was present in andiroba, avocado, canola, copaiba, olive, palm, pequi, and pracaxi oils and featured prominently in olive oil (75.8%). Linoleic acid (57.09% ± 8.47%) was present in corn, cottonseed, grapeseed, passion fruit, and sunflower oils and in mixed oils (olive with soybean and sunflower with corn and canola).

CONCLUSIONS

Most of the vegetable oils tested are products of plants from tropical climates, where they are abundant and easy to cultivate. It is possible that a balanced composition of fatty acids obtained from natural sources could be an effective alternative treatment for wounds.

摘要

目的

评估在巴西市场销售的植物油与用于治疗伤口的参考保健产品的脂肪酸组成之间的相似性。

方法

使用气相色谱-质谱联用和火焰离子化检测评估 21 种植物油中的脂肪酸相对含量。

主要结果

研究中的油与参考产品（辛酸，18.8%；癸酸，17.4%；油酸，27.5%；亚油酸，28.1%）具有相似的脂肪酸组成。所有测试的植物油中均存在辛酸（10.45%±0.07%）、癸酸（5.8%±0.75%）、月桂酸（45.63%±0.93%）和肉豆蔻酸（16.33%±2.23%）。在巴西坚果、鳄梨、菜籽油、库帕巴、橄榄油、棕榈、培古西油和普拉卡西油中均存在油酸（52.94%±12.54%），且橄榄油中含量较高（75.8%）。在玉米油、棉籽油、葡萄籽油、西番莲油和葵花籽油以及混合油（橄榄油与大豆、葵花籽油与玉米和菜籽油）中均存在亚油酸（57.09%±8.47%）。