Merckling-Almeida da Silva Luana, Merckling Nicolas, Bigi Enrico, Cunha de Melo Katiane, Popa Iuliana
Institut Médical de Champel, 1206 Geneva, Switzerland.
Dumato Ltd.-Specialists in Amazonian Natural Products, 1260 Nyon, Switzerland.
Metabolites. 2025 Aug 19;15(8):554. doi: 10.3390/metabo15080554.
A great biodiversity of compounds from Brazilian medicinal plants are considered to be a promising source for biological activities in the cosmetics and pharmaceuticals sectors. Lipids and mainly fatty acids from Brazilian medicinal plants and their bioactive components are promising ingredients with proven diverse biological activities. To undertake a review of some rare oils of Brazilian medicinal plants with corroborated biological activities, we selected data from the scientific literature reporting the efficacy of plants used in folk medicine as antioxidant, anti-inflammatory or other types of activity of their oil phases extracts and isolated fatty acids. A search of the literature was undertaken by using the following web tools: Web of Science, SciFinder, Pub-Med and ScienceDirect. The terms "biological activity", "anti-inflammatory", "açai oil, andiroba oil, bacuri butter, buriti oil, cupuaçu butter and pracaxi oil", and "free fatty acids" and "Amazonian plant oils" were used as keywords in the search engines. The Tropicos and Reflora websites were used to verify the origin of the plants, and only native plants from Brazil were included in this review. Only the publications reporting the use of well-accepted scientific protocols to corroborate the potential biological activities of rare oils of Amazonian plants were considered. We selected 6 Brazilian medicinal plant oils extracts (acai, andiroba, bacuri, buriti, cupuaçu, pracaxi) with multiple biological activities. The observations were presented as a function of the oil origin and the most important biological activities were detailed. The collected data on the rare oils from Amazonian plants, in the form of crude extract and/or isolated compounds, showed significant biological activities involving different mechanisms of action, indicating that these oils could be an important source of lipids with biological activity.
巴西药用植物中的大量化合物具有生物多样性，被认为是化妆品和制药行业生物活性的一个有前景的来源。巴西药用植物中的脂质，主要是脂肪酸及其生物活性成分，是具有多种已证实生物活性的有前景的成分。为了对一些具有确凿生物活性的巴西药用植物稀有油进行综述，我们从科学文献中选取了数据，这些文献报道了民间医学中使用的植物作为抗氧化剂、抗炎剂或其油相提取物及分离脂肪酸的其他类型活性的功效。通过使用以下网络工具进行文献检索：科学网、SciFinder、PubMed和ScienceDirect。在搜索引擎中使用了“生物活性”“抗炎”“阿萨伊油、印加果油、巴西栗脂、伯蒂榈油、可可脂和普拉卡希油”以及“游离脂肪酸”和“亚马逊植物油”等术语作为关键词。使用Tropicos和Reflora网站核实植物的来源，本综述仅纳入来自巴西的本土植物。仅考虑那些报告使用公认科学方案来证实亚马逊植物稀有油潜在生物活性的出版物。我们选择了6种具有多种生物活性的巴西药用植物油提取物（阿萨伊、印加果、巴西栗、伯蒂榈、可可、普拉卡希）。观察结果以油的来源为函数呈现，并详细阐述了最重要的生物活性。以粗提物和/或分离化合物形式收集的关于亚马逊植物稀有油的数据显示出涉及不同作用机制的显著生物活性，表明这些油可能是具有生物活性脂质的重要来源。
