Wicks I P, Wong D, McCullagh R B, Fleming A
Department of Rheumatology, Prince Henry Hospital, Sydney, Australia.
Ann Rheum Dis. 1988 May;47(5):421-2. doi: 10.1136/ard.47.5.421.
A patient with seropositive, nodular rheumatoid arthritis (RA) developed contact allergy to gold jewellery following a severe skin rash which occurred after 13 weeks of treatment with sodium aurothiomalate. Patch testing confirmed that the contact allergy was due to gold. This is the first proved case of contact allergy to gold or any other compound initiated by systemic administration of the allergen.
一名血清反应阳性的结节性类风湿关节炎（RA）患者在用硫代苹果酸金钠治疗13周后出现严重皮疹，之后对金首饰产生接触性过敏。斑贴试验证实接触性过敏是由金引起的。这是首例经证实因全身性给予变应原而引发对金或任何其他化合物接触性过敏的病例。
