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金疗法的另一种危害?

Another hazard of gold therapy?

作者信息

Fulton R A, Sturrock R D, Capell H

出版信息

Ann Rheum Dis. 1982 Feb;41(1):100-1. doi: 10.1136/ard.41.1.100.

DOI:10.1136/ard.41.1.100
PMID:6802079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1000874/
Abstract

A patient with seropositive rheumatoid developed a bullous eruption localised to the jewellery areas 12 hours after a test dose of sodium aurothiomalate (Myocrisin). Investigation showed that she was allergic to nickel rather than gold. Small quantities of nickel were found in the Myocrisin solution after a short contact with a metal needle, suggesting an explanation for the reaction.

摘要

一名血清阳性类风湿性关节炎患者在注射试验剂量的硫代苹果酸金钠(Myocrisin)12小时后,在佩戴首饰的部位出现大疱性皮疹。调查显示她对镍过敏而非对金过敏。在与金属针短暂接触后,在硫代苹果酸金钠溶液中发现了少量镍,这为该反应提供了一种解释。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/625a/1000874/24980c2cf619/annrheumd00108-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/625a/1000874/24980c2cf619/annrheumd00108-0108-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/625a/1000874/24980c2cf619/annrheumd00108-0108-a.jpg

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引用本文的文献

1
Another hazard of gold therapy.金疗法的另一个危害。
Ann Rheum Dis. 1982 Aug;41(4):436. doi: 10.1136/ard.41.4.436.
2
Contact allergy to gold after systemic administration of gold for rheumatoid arthritis.类风湿关节炎患者全身应用金制剂后发生的金接触性过敏。
Ann Rheum Dis. 1988 May;47(5):421-2. doi: 10.1136/ard.47.5.421.

本文引用的文献

1
[Allergic reactions to nickel from infusion equipment].[输液设备镍过敏反应]
Ned Tijdschr Geneeskd. 1977 Jan 1;121(1):4-9.
2
Local gold toxicity.局部金中毒
Br Med J. 1976 Nov 27;2(6047):1294. doi: 10.1136/bmj.2.6047.1294.