Nema Juhi, Sundrani Deepali, Joshi Sadhana
Mother and Child Health, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University) , Pune , India.
Hypertens Pregnancy. 2019 Nov;38(4):201-207. doi: 10.1080/10641955.2019.1647231. Epub 2019 Jul 24.
: Vitamin D plays a key role during pregnancy and is involved in implantation and maintenance of pregnancy. Its deficiency is associated with pregnancy complications like preeclampsia, characterized by abnormal angiogenesis.: The current article summarises studies examining the role of vitamin D in pregnancy, with special emphasis on preeclampsia.: An imbalance in pro- and anti-angiogenic factors is reported in women with preeclampsia. Cell culture studies have demonstrated that vitamin D can influence the process of angiogenesis. However, the role of maternal vitamin D in influencing placental angiogenesis in preeclampsia is unclear and needs to be explored.
维生素D在孕期发挥关键作用，参与妊娠的着床与维持。其缺乏与子痫前期等妊娠并发症相关，子痫前期的特征是血管生成异常。本文总结了研究维生素D在孕期作用的相关研究，特别强调了子痫前期。据报道，子痫前期女性体内促血管生成因子和抗血管生成因子失衡。细胞培养研究表明，维生素D可影响血管生成过程。然而，母体维生素D在子痫前期影响胎盘血管生成中的作用尚不清楚，有待探索。
