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从实时肿瘤治疗(RTT)角度看磁共振引导放射治疗的临床应用

The clinical introduction of MR-guided radiation therapy from a RTT perspective.

作者信息

Botman R, Tetar S U, Palacios M A, Slotman B J, Lagerwaard F J, Bruynzeel A M E

机构信息

Dept. of Radiation Oncology, Amsterdam UMC, location VU University Medical Center, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.

出版信息

Clin Transl Radiat Oncol. 2019 Apr 26;18:140-145. doi: 10.1016/j.ctro.2019.04.019. eCollection 2019 Sep.

Abstract

The latest development in radiation oncology departments towards high precision and adaptive radiation therapy is the clinical introduction of magnetic resonance image guided radiation therapy (MRgRT). Early 2016, patient treatment using MRgRT was started at Amsterdam UMC, location VU University Medical Center. Introducing this novel technique in clinical practice requires thorough preparation with regard to important topics, such as MR-safety and training, equipping the treatment vault and console room, development of MRgRT workflow and logistical issues. Certainly when MRgRT is combined with daily plan adaptation, this indicates adjusting existing workflows and protocols. The MRgRT workflow requires a multidisciplinary process, and while each discipline has had its own tasks and responsibilities, with growing clinical experience there has been a shift towards RTT responsibilities. In this overview we discuss preclinical training and preparation for the implementation of (adaptive) MRgRT, with a particular focus on the perspective of RTTs. Although the reviewed logistics are partly the result of the decision to perform daily plan re-optimization, our experience can be extrapolated to implementation of alternative approaches for MRgRT.

摘要

放射肿瘤学部门向高精度和自适应放射治疗发展的最新成果是磁共振成像引导放射治疗(MRgRT)在临床中的应用。2016年初,阿姆斯特丹大学医学中心(位于VU大学医学中心)开始使用MRgRT对患者进行治疗。在临床实践中引入这项新技术需要在重要课题上进行充分准备,比如磁共振安全与培训、治疗室和控制台室的设备配备、MRgRT工作流程的制定以及后勤问题。当MRgRT与每日计划调整相结合时,这意味着要调整现有的工作流程和协议。MRgRT工作流程需要多学科协作,虽然每个学科都有自己的任务和职责,但随着临床经验的积累,职责逐渐向放射治疗技师(RTT)转移。在本综述中,我们讨论了(自适应)MRgRT实施前的临床培训和准备工作,特别关注放射治疗技师的视角。尽管所审查的后勤工作部分是由于决定进行每日计划重新优化的结果,但我们的经验可以推广到MRgRT其他替代方法的实施中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d7e/6630155/4a770f34662a/gr1.jpg

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