Jalalahmadi Golnaz, Helguera María, Mix Doran S, Hodis Simona, Richards Michael S, Stoner Michael C, Linte Cristian A
Chester F. Carlson Center for Imaging Science, Rochester Institute of Technology, Rochester, USA.
Instituto Tecnológico José Mario Molina Pasquel y Henríquez - Unidad Lagos de Moreno, Jalisco, México.
Proc IEEE West N Y Image Signal Process Workshop. 2018 Oct;2018. doi: 10.1109/WNYIPW.2018.8576453. Epub 2018 Dec 17.
Abdominal aortic aneurysms, which consist of dilatations of the infra-renal aorta by at least 1.5 times of its normal diameter, are becoming a leading cause of death worldwide. Rupture often occurs unexpectedly, before a repair procedure is conducted. The AAA maximum diameter has been used as a clinical criterion to monitor AAA severity. However, assessment of AAA rupture risk requires knowledge of wall stress and wall strength at the potential rupture location. We conducted a study on 37 patient specific CT datasets to investigate the benefits of using peak wall stress instead of D for AAA rupture severity. Correlation between PWS and 24 geometric indices and biomechanical factors was studied where eleven of them showed a statistically significant correlation with PWS. A Finite Element Analysis Rupture Index was used to conclude that the use of as a single predictor of AAA behavior and severity may be insufficient based on our patient population with a D smaller than the 5.5 cm, clinically recommended repair threshold.
腹主动脉瘤是指肾下腹主动脉扩张至正常直径的至少1.5倍,它正成为全球主要的死亡原因之一。破裂常常在进行修复手术之前意外发生。腹主动脉瘤的最大直径已被用作监测腹主动脉瘤严重程度的临床标准。然而,评估腹主动脉瘤破裂风险需要了解潜在破裂部位的壁应力和壁强度。我们对37个患者特异性CT数据集进行了一项研究,以调查使用峰值壁应力而非直径来评估腹主动脉瘤破裂严重程度的益处。研究了峰值壁应力与24个几何指标和生物力学因素之间的相关性,其中11个指标与峰值壁应力具有统计学上的显著相关性。基于我们所研究的腹主动脉瘤直径小于临床推荐的5.5 cm修复阈值的患者群体,使用有限元分析破裂指数得出结论:仅将直径作为腹主动脉瘤行为和严重程度的单一预测指标可能并不充分。