Hamedani Ali G, Pelak Victoria S
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St., 3 W. Gates Bldg., Philadelphia, PA, 19104, USA.
Departments of Neurology and Ophthalmology, The Rocky Mountain Lions Eye Institute, University of Colorado School of Medicine, Aurora, CO, USA.
Curr Treat Options Neurol. 2019 Jul 25;21(9):41. doi: 10.1007/s11940-019-0582-1.
To perform a systematic review of diagnostic criteria for the Charles Bonnet syndrome (CBS).
Across 33 studies that specified diagnostic criteria for CBS, hallucinations and vision loss were a common requirement, but there was considerable heterogeneity regarding hallucination properties (i.e., formed vs. unformed) and the severity of vision loss. The exclusion of confounding neuropsychiatric disorders was also common, but specific disorders and their method of ascertainment were variable. There is considerable diagnostic heterogeneity for CBS in the literature. These differences have important implications for the results of observational and interventional studies of CBS and highlight the need for unified diagnostic criteria.
对查尔斯·邦尼特综合征（CBS）的诊断标准进行系统评价。
在33项明确了CBS诊断标准的研究中，幻觉和视力丧失是常见的必要条件，但在幻觉特征（即成形与不成形）和视力丧失的严重程度方面存在相当大的异质性。排除混杂的神经精神疾病也很常见，但具体疾病及其确定方法各不相同。文献中CBS的诊断存在相当大的异质性。这些差异对CBS的观察性和干预性研究结果具有重要意义，并突出了统一诊断标准的必要性。
