Neurotrauma Impact Science Laboratory, School of Human Kinetics, University of Ottawa, Ontario, Canada.
J Athl Train. 2019 Jul;54(7):765-771. doi: 10.4085/1062-6050-253-18. Epub 2019 Jul 25.
Loss of consciousness (LOC) and impact seizures associated with concussion represent different clinical presentations of concussion; however, they are often investigated and treated similarly. The biomechanical parameters differentiating these 2 distinct signs of injury are poorly described.
To differentiate between cases of concussions with LOC and those with impact seizures by comparing the impact velocity, peak linear and peak rotational acceleration, as well as brain tissue deformation in the cerebral cortex, white matter, brainstem, cerebellum, thalamus, and corpus callosum.
Descriptive laboratory study.
Elite American football players who sustained an LOC (n = 20) or impact seizures (n = 21).
MAIN OUTCOME MEASURE(S): Impact velocity, peak linear and peak rotational acceleration, maximum principal strain, cumulative strain damage measure at 10%, and strain rate (SR).
The SR in the cerebral white matter was greater in the LOC group than in the impact-seizure group. Similar trends were observed for SRs in the cerebral cortex, brainstem, and corpus callosum. No differences were present between groups for the other variables in this study.
A lower SR in certain brain regions helps to explain why motor function is preserved and can be observed in patients with impact seizures versus LOC from concussive injuries.
意识丧失（LOC）和冲击性癫痫发作与脑震荡有关，代表脑震荡的不同临床表现；然而，它们通常以类似的方式进行调查和治疗。区分这两种不同损伤迹象的生物力学参数描述得很差。
通过比较冲击速度、线性和旋转加速度峰值以及大脑皮层、白质、脑干、小脑、丘脑和胼胝体的脑组织变形，区分伴有 LOC 的脑震荡病例和伴有冲击性癫痫发作的脑震荡病例。
描述性实验室研究。
遭受 LOC（n = 20）或冲击性癫痫发作（n = 21）的精英美式足球运动员。
冲击速度、线性和旋转加速度峰值、最大主应变、10%累积应变损伤量和应变率（SR）。
LOC 组大脑白质中的 SR 大于冲击性癫痫发作组。在大脑皮层、脑干和胼胝体中也观察到类似的 SR 趋势。在本研究的其他变量中，两组之间没有差异。
某些脑区的较低 SR 有助于解释为什么在冲击性癫痫发作而不是伴有 LOC 的脑震荡损伤中保留了运动功能并可以观察到。
