Chan Melissa Mei Hsia, Thomas Akshay S, Yoon Stephen P, Leitner Diana, Fekrat Sharon
Ophthalmic Surg Lasers Imaging Retina. 2019 Jul 1;50(7):444-449. doi: 10.3928/23258160-20190703-06.
To compare risk factors in patients with a central retinal vein occlusion (CRVO) in the first eye and a subsequent retinal vein occlusion (RVO) in the fellow eye versus those with only unilateral CRVO.
Records of patients who presented to the Duke Eye Center with unilateral CRVO were evaluated. Logistic regression models were performed to identify potential covariates of subsequent development of RVO in the fellow eye.
Of the 287 patients with CRVO in one eye, 31 (10.8%) developed an RVO in the fellow eye during a mean ± standard deviation follow-up of 36.7 months ± 38.86 months. The conversion rate of unilateral-to-bilateral RVO was 3.4% per year. Several comorbidities were observed to be unique to 25.8% of patients with bilateral RVO. Patients who used oral pentoxifylline (P = .008) or those who had an ischemic CRVO in the first eye (P = .001) were less likely to develop an RVO in the fellow eye.
This information may be used to develop a predictive model to assess the risk of developing bilateral RVO in patients with unilateral CRVO. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:444-449.].
比较第一只眼发生视网膜中央静脉阻塞（CRVO）且对侧眼随后发生视网膜静脉阻塞（RVO）的患者与仅患单侧CRVO患者的危险因素。
对就诊于杜克眼科中心的单侧CRVO患者的记录进行评估。采用逻辑回归模型确定对侧眼随后发生RVO的潜在协变量。
在287例单眼患CRVO的患者中，在平均±标准差为36.7个月±38.86个月的随访期间，31例（10.8%）对侧眼发生了RVO。单侧RVO向双侧RVO的转化率为每年3.4%。观察到几种合并症在25.8%的双侧RVO患者中是独有的。使用口服己酮可可碱的患者（P = .008）或第一只眼发生缺血性CRVO的患者（P = .001）对侧眼发生RVO的可能性较小。
该信息可用于建立预测模型，以评估单侧CRVO患者发生双侧RVO的风险。[《眼科手术、激光与视网膜成像》。2019；50：444 - 449。]
