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双眼视网膜静脉阻塞的发病情况、发病时间及危险因素。

The Incidence, Time to Development, and Risk Factors for Fellow Eye Retinal Vein Occlusions.

出版信息

Ophthalmic Surg Lasers Imaging Retina. 2023 Aug;54(8):471-476. doi: 10.3928/23258160-20230726-03. Epub 2023 Aug 1.

DOI:10.3928/23258160-20230726-03
PMID:37603786
Abstract

BACKGROUND AND OBJECTIVE

Little is known about factors affecting risk or time to development of fellow eye retinal vein occlusion (RVO). The purpose of this study was to examine the incidence and risk factors for fellow eye RVO.

PATIENTS AND METHODS

This was a retrospective case-control study comparing unilateral and fellow eye RVO patients. This study was exempt by the Cleveland Clinic Institutional Review Board.

RESULTS

Out of 1,083 patients, fellow eye RVO had a cumulative incidence of 3.6% (95% CI 2.61, 4.94) with a median time to development of 18 months (95% CI 6.0, 28.0). Fellow eye disease was associated with multiple characteristics including chronic kidney disease (odds ratio [OR] 3.78, 95% CI 1.89 to 7.55) and diabetic retinopathy (3.18, 1.57 to 6.44).

CONCLUSION

While fellow eye RVO is relatively rare, it typically occurs within the first few years following initial diagnosis. Multiple characteristics were associated with fellow eye disease and time to onset. .

摘要

背景与目的

关于影响对侧眼视网膜静脉阻塞(RVO)风险或发病时间的因素知之甚少。本研究旨在探讨对侧眼 RVO 的发病情况和危险因素。

患者与方法

这是一项单侧和对侧眼 RVO 患者的回顾性病例对照研究。本研究经克利夫兰诊所机构审查委员会豁免。

结果

在 1083 例患者中,对侧眼 RVO 的累积发病率为 3.6%(95%CI 2.61,4.94),中位发病时间为 18 个月(95%CI 6.0,28.0)。对侧疾病与多种特征相关,包括慢性肾脏病(比值比[OR]3.78,95%CI 1.89 至 7.55)和糖尿病视网膜病变(3.18,1.57 至 6.44)。

结论

尽管对侧眼 RVO 相对少见,但通常在初次诊断后的几年内发生。多种特征与对侧疾病和发病时间相关。

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