ETH Zurich, Lab. Phys. Chem., Vladimir-Prelog-Weg 2, 8093 Zurich, Switzerland.
J Magn Reson. 2019 Sep;306:36-41. doi: 10.1016/j.jmr.2019.07.008. Epub 2019 Jul 13.
Complexity of paramagnetic catalysts and materials increases, and the same applies to systems targeted by integrative structural biology. Hence, EPR spectroscopists must find ways to enhance information content of their data. I argue that a third major wave of method development in EPR spectroscopy, which is triggered by recent advances in digital electronics and computing, can achieve this. Transfer of NMR methods to EPR will go on, but part of the new EPR methodology will depend on completely new concepts.
顺磁催化剂和材料的复杂性增加，综合结构生物学所针对的系统也是如此。因此，电子顺磁共振（EPR）光谱学家必须找到方法来提高其数据的信息量。我认为，由数字电子和计算的最新进展引发的 EPR 光谱学的第三次主要方法发展浪潮可以实现这一目标。NMR 方法将继续转移到 EPR，但部分新的 EPR 方法将取决于全新的概念。
