Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA
Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia Health System, Charlottesville, Virginia, USA.
Antimicrob Agents Chemother. 2019 Jul 25;63(8). doi: 10.1128/AAC.00029-19. Print 2019 Aug.
The recent development of new antimicrobials active against carbapenemase-producing (CPE) has brought new hope for the treatment of infections due to these organisms. However, the evolving epidemiology of bacteria with carbapenemases may complicate management, as providers are faced with treating patients colonized by bacteria producing multiple carbapenemases. Here, we present the clinical course and treatment of bacteremia in a cirrhotic patient known to be colonized with both - and -carrying organisms.
最近开发出了一些新型针对产碳青霉烯酶（CPE）的抗菌药物，为治疗这些病原体引起的感染带来了新的希望。然而，具有碳青霉烯酶的细菌的流行病学正在不断演变，这可能会使治疗变得复杂，因为临床医生需要治疗那些定植了产多种碳青霉烯酶细菌的患者。在这里，我们介绍了一位已知定植有携带 - 和 - 碳青霉烯酶的生物体的肝硬化患者的菌血症临床病程和治疗情况。
