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Stingless bee honey protects against lipopolysaccharide induced-chronic subclinical systemic inflammation and oxidative stress by modulating Nrf2, NF-κB and p38 MAPK.无刺蜂蜂蜜通过调节Nrf2、NF-κB和p38丝裂原活化蛋白激酶，预防脂多糖诱导的慢性亚临床全身炎症和氧化应激。
Nutr Metab (Lond). 2019 Feb 27;16:15. doi: 10.1186/s12986-019-0341-z. eCollection 2019.
2
Fisetin ameliorates oxidative stress, inflammation and apoptosis in diabetic cardiomyopathy.非瑟酮可改善糖尿病心肌病中的氧化应激、炎症和细胞凋亡。
Life Sci. 2019 Mar 15;221:83-92. doi: 10.1016/j.lfs.2019.02.017. Epub 2019 Feb 8.
3
Umbelliferone Ameliorates CCl-Induced Liver Fibrosis in Rats by Upregulating PPARγ and Attenuating Oxidative Stress, Inflammation, and TGF-β1/Smad3 Signaling.芒柄花素通过上调 PPARγ 并减轻氧化应激、炎症和 TGF-β1/Smad3 信号通路来改善 CCl4 诱导的大鼠肝纤维化。
Inflammation. 2019 Jun;42(3):1103-1116. doi: 10.1007/s10753-019-00973-8.
4
The Role of Nrf2 Signaling in PPAR/-Mediated Vascular Protection against Hyperglycemia-Induced Oxidative Stress.Nrf2 信号在过氧化物酶体增殖物激活受体 γ 介导的血管对高血糖诱导的氧化应激的保护作用中的作用。
Oxid Med Cell Longev. 2018 Jun 25;2018:5852706. doi: 10.1155/2018/5852706. eCollection 2018.
5
Commiphora molmol protects against methotrexate-induced nephrotoxicity by up-regulating Nrf2/ARE/HO-1 signaling.没药通过上调 Nrf2/ARE/HO-1 信号通路保护氨甲喋呤诱导的肾毒性。
Biomed Pharmacother. 2018 Oct;106:499-509. doi: 10.1016/j.biopha.2018.06.171. Epub 2018 Jul 11.
6
Ginger alleviates hyperglycemia-induced oxidative stress, inflammation and apoptosis and protects rats against diabetic nephropathy.生姜可减轻高血糖引起的氧化应激、炎症和细胞凋亡，对糖尿病肾病大鼠具有保护作用。
Biomed Pharmacother. 2018 Oct;106:381-389. doi: 10.1016/j.biopha.2018.06.148. Epub 2018 Jul 11.
7
Umbelliferone prevents oxidative stress, inflammation and hematological alterations, and modulates glutamate-nitric oxide-cGMP signaling in hyperammonemic rats.芒柄花素可预防氧化应激、炎症和血液学改变，并调节高血氨症大鼠中的谷氨酸-一氧化氮-cGMP 信号通路。
Biomed Pharmacother. 2018 Jun;102:392-402. doi: 10.1016/j.biopha.2018.03.104. Epub 2018 Mar 22.
8
Olive oil and leaf extract prevent fluoxetine-induced hepatotoxicity by attenuating oxidative stress, inflammation and apoptosis.橄榄油和叶提取物通过减轻氧化应激、炎症和细胞凋亡来预防氟西汀诱导的肝毒性。
Biomed Pharmacother. 2018 Feb;98:446-453. doi: 10.1016/j.biopha.2017.12.101. Epub 2017 Dec 27.
9
Hesperidin protects against chemically induced hepatocarcinogenesis via modulation of Nrf2/ARE/HO-1, PPARγ and TGF-β1/Smad3 signaling, and amelioration of oxidative stress and inflammation.橙皮苷通过调节 Nrf2/ARE/HO-1、PPARγ 和 TGF-β1/Smad3 信号通路，以及改善氧化应激和炎症，来防止化学诱导的肝癌发生。
Chem Biol Interact. 2017 Nov 1;277:146-158. doi: 10.1016/j.cbi.2017.09.015. Epub 2017 Sep 19.
10
Possible involvement of Nrf2 and PPARγ up-regulation in the protective effect of umbelliferone against cyclophosphamide-induced hepatotoxicity.伞形酮对环磷酰胺诱导的肝毒性的保护作用可能与 Nrf2 和 PPARγ 的上调有关。
Biomed Pharmacother. 2017 Feb;86:297-306. doi: 10.1016/j.biopha.2016.12.047. Epub 2016 Dec 21.

Modulating Oxidative Stress in Drug-Induced Injury and Metabolic Disorders: The Role of Natural and Synthetic Antioxidants.

作者信息

Mahmoud Ayman M, Wilkinson Fiona L, Sandhu Mansur A, Dos Santos Julia M, Alexander M Yvonne

机构信息

Physiology Division, Zoology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.

Cardiovascular Science, The Centre for Bioscience, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK.

出版信息

Oxid Med Cell Longev. 2019 Jun 27;2019:3206401. doi: 10.1155/2019/3206401. eCollection 2019.

DOI:10.1155/2019/3206401
PMID:31346360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6620855/
Abstract
摘要