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采用32毫米股骨头的骨水泥型埃克塞特全髋关节置换术,使用高度交联聚乙烯:年龄是否会影响功能结果、满意度、活动能力、假体柄移位及假体周围骨密度?

Cemented Exeter total hip arthroplasty with a 32 mm head on highly crosslinked polyethylene: Does age influence functional outcome, satisfaction, activity, stem migration, and periprosthetic bone mineral density?

作者信息

Clement N D, Bardgett M, Merrie K, Furtado S, Bowman R, Langton D J, Deehan D J, Holland J

机构信息

Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne, UK.

Northern Retrieval Registry, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK.

出版信息

Bone Joint Res. 2019 Jul 5;8(6):275-287. doi: 10.1302/2046-3758.86.BJR-2018-0300.R1. eCollection 2019 Jun.

DOI:10.1302/2046-3758.86.BJR-2018-0300.R1
PMID:31346456
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6609865/
Abstract

OBJECTIVES

Our primary aim was to describe migration of the Exeter stem with a 32 mm head on highly crosslinked polyethylene and whether this is influenced by age. Our secondary aims were to assess functional outcome, satisfaction, activity, and bone mineral density (BMD) according to age.

PATIENTS AND METHODS

A prospective cohort study was conducted. Patients were recruited into three age groups: less than 65 years (n = 65), 65 to 74 years (n = 68), and 75 years and older (n = 67). There were 200 patients enrolled in the study, of whom 115 were female and 85 were male, with a mean age of 69.9 years (sd 9.5, 42 to 92). They were assessed preoperatively, and at three, 12 and, 24 months postoperatively. Stem migration was assessed using Einzel-Bild-Röntgen-Analyse (EBRA). Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Harris Hip Score (HHS), Hip Disability and Osteoarthritis Outcome Score (HOOS), EuroQol-5 domains questionnaire (EQ-5D), short form-36 questionnaire (SF-36,) and patient satisfaction were used to assess outcome. The Lower Extremity Activity Scale (LEAS), Timed Up and Go (TUG) test, and activPAL monitor (energy expelled, time lying/standing/walking and step count) were used to assess activity. The BMD was assessed in Gruen and Charnley zones.

RESULTS

Mean varus/valgus tilt was -0.77⁰ and axial subsidence was -1.20 mm. No significant difference was observed between age groups (p ⩾ 0.07). There was no difference according to age group for postoperative WOMAC (p ⩾ 0.11), HHS (p ⩾ 0.06), HOOS (p ⩾ 0.46), EQ-5D (p ⩾ 0.38), patient satisfaction (p ⩾ 0.05), or activPAL (p ⩾ 0.06). Patients 75 years and older had a worse SF-36 physical function (p = 0.01) and physical role (p = 0.03), LEAS score (p < 0.001), a shorter TUG (p = 0.01), and a lower BMD in Charnley zone 1 (p = 0.02).

CONCLUSION

Exeter stem migration is within normal limits and is not influenced by age group. Functional outcome, patient satisfaction, activity level, and periprosthetic BMD are similar across all age groups.: N. D. Clement, M. Bardgett, K. Merrie, S. Furtado, R. Bowman, D. J. Langton, D. J. Deehan, J. Holland. Cemented Exeter total hip arthroplasty with a 32 mm head on highly crosslinked polyethylene: Does age influence functional outcome, satisfaction, activity, stem migration, and periprosthetic bone mineral density? 2019;8:275-287. DOI: 10.1302/2046-3758.86.BJR-2018-0300.R1.

摘要

目的

我们的主要目的是描述采用高度交联聚乙烯、头直径为32毫米的埃克塞特柄的移位情况,以及年龄是否会对其产生影响。我们的次要目的是根据年龄评估功能结果、满意度、活动情况和骨密度(BMD)。

患者与方法

进行了一项前瞻性队列研究。患者被分为三个年龄组:小于65岁(n = 65)、65至74岁(n = 68)以及75岁及以上(n = 67)。该研究共纳入200例患者,其中女性115例,男性85例,平均年龄69.9岁(标准差9.5,42至92岁)。对他们在术前以及术后3个月、12个月和24个月进行评估。采用 Einzel-Bild-Röntgen-Analyse(EBRA)评估柄的移位情况。使用西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、Harris髋关节评分(HHS)、髋关节功能障碍和骨关节炎结果评分(HOOS)、欧洲五维健康量表(EQ-5D)、简明健康调查问卷(SF-36)以及患者满意度来评估结果。采用下肢活动量表(LEAS)、计时起立行走测试(TUG)以及activPAL监测仪(能量消耗、躺卧/站立/行走时间和步数)来评估活动情况。在Gruen和Charnley区域评估骨密度。

结果

平均内翻/外翻倾斜为-0.77°,轴向下沉为-1.20毫米。各年龄组之间未观察到显著差异(p⩾0.07)。术后WOMAC(p⩾0.11)、HHS(p⩾0.06)、HOOS(p⩾0.46)、EQ-5D(p⩾0.38)、患者满意度(p⩾0.05)或activPAL(p⩾0.06)在各年龄组之间也无差异。75岁及以上患者的SF-36身体功能(p = 0.01)和身体角色(p = 0.03)、LEAS评分(p < 0.001)、TUG时间较短(p = 0.01),且Charnley区域1的骨密度较低(p = 0.02)。

结论

埃克塞特柄的移位在正常范围内,不受年龄组影响。所有年龄组的功能结果、患者满意度、活动水平和假体周围骨密度相似。作者:N. D. 克莱门特、M. 巴德gett、K. 梅里、S. 弗尔塔多、R. 鲍曼、D. J. 兰顿、D. J. 迪恩、J. 霍兰德。采用高度交联聚乙烯、头直径为32毫米的骨水泥型埃克塞特全髋关节置换术:年龄是否会影响功能结果、满意度、活动、柄的移位以及假体周围骨密度?2019年;8卷:275 - 287页。DOI:10.1302/2046 - 3758.86.BJR - 2018 - 0300.R1 。

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