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基于日本全国数据库的胃肠外科手术后预测术后肺炎的风险计算器

Risk calculator for predicting postoperative pneumonia after gastroenterological surgery based on a national Japanese database.

作者信息

Takesue Yoshio, Miyata Hiroaki, Gotoh Mitsukazu, Wakabayashi Go, Konno Hiroyuki, Mori Masaki, Kumamaru Hiraku, Ueda Takashi, Nakajima Kazuhiko, Uchino Motoi, Seto Yasuyuki

机构信息

The Japanese Society of Gastroenterological Surgery Tokyo Japan.

National Clinical Database Tokyo Japan.

出版信息

Ann Gastroenterol Surg. 2019 Apr 22;3(4):405-415. doi: 10.1002/ags3.12248. eCollection 2019 Jul.

Abstract

BACKGROUND

The aim of the present study was to develop a risk calculator predictive of postoperative pneumonia in patients undergoing gastroenterological surgery.

METHODS

We analyzed data from 382 124 patients undergoing eight main gastroenterological surgeries between 2011 and 2013 using the National Clinical Database in Japan. A risk model was developed using multivariate logistic regression analysis with patient data from 2011 to 2012 (n = 247 604) and validated using data from 2013 (n = 134 520).

RESULTS

Pneumonia was observed in 11 105 patients (2.9%). After the input of significant primary disease and surgical procedures, 18 patient characteristics including gender, chronic obstructive pulmonary disease, sepsis, and need for any assistance in the activities of daily living, six laboratory parameters, and two intraoperative factors were used for risk calculation. Area under the receiver-operating characteristic curve was 0.822 (95% confidence interval, 0.817-0.826) in the derivation group and 0.826 (0.819-0.832) in the validation group.

CONCLUSION

The risk calculator accurately predicted the occurrence of pneumonia following gastroenterological surgery.

摘要

背景

本研究旨在开发一种风险计算器,用于预测接受胃肠外科手术患者的术后肺炎。

方法

我们使用日本国家临床数据库分析了2011年至2013年间接受八种主要胃肠外科手术的382124例患者的数据。利用2011年至2012年患者数据(n = 247604)通过多因素逻辑回归分析建立风险模型,并使用2013年数据(n = 134520)进行验证。

结果

11105例患者(2.9%)发生肺炎。在输入显著的原发性疾病和手术操作后,18项患者特征(包括性别、慢性阻塞性肺疾病、脓毒症以及日常生活活动是否需要任何协助)、6项实验室参数和2项术中因素用于风险计算。受试者工作特征曲线下面积在推导组为0.822(95%置信区间,0.817 - 0.826),在验证组为0.826(0.819 - 0.832)。

结论

该风险计算器能准确预测胃肠外科手术后肺炎的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b8b/6635692/e4ceb87f6be1/AGS3-3-405-g001.jpg

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