Guo Xiaohong, Zhou Yao, Gu Chenyang, Wu Yingjie, Liu Hui, Chang Qing, Lei Bo, Wang Min
Henan Eye Hospital, Henan Eye Institute, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou 450003, China.
Department of Ophthalmology and Visual Science, Eye, Ear, Nose and Throat Hospital, Shanghai Medical College of Fudan University, Shanghai 200031, China.
J Clin Med. 2022 Nov 26;11(23):6994. doi: 10.3390/jcm11236994.
To investigate the features of choroidal caverns in diverse retinal diseases with swept-source optical coherence tomography (SS-OCT).
Subjects with normal eyes, retinitis pigmentosa (RP), wet age-related macular degeneration (wAMD), acute central serous chorioretinopathy (CSC), or chronic CSC were enrolled. The characteristics of choroidal caverns were evaluated with SS-OCT. The prevalence of choroidal caverns in retinal diseases and the correlations between the number, width and depth of choroidal caverns with the thickness of choroid were analyzed.
Among 315 eyes of 220 subjects, choroidal caverns were found in 110 eyes (34.9%). Choroidal caverns were divided into two categories based on their location and size. Type I was small and usually lobulated, presented in the choroidal capillary and Sattler's layers. Type II was larger, usually isolated, and presented in the Sattler's and Haller's layers. The prevalence of type I in subjects with normal eyes, RP, wAMD, acute CSC, or chronic CSC was 17.4%, 19.6%, 1.6%, 32.8%, and 85.2%, respectively, while that of type II was 0%, 0%, 21.3%, 13.8%, and 53.7%, respectively. The number, width, and thickness of type II choroidal caverns correlated positively with macular choroidal thickness.
Choroidal caverns could be divided into two categories. Type II choroidal caverns appeared associated with the pachychoroid spectrum and RPE atrophic diseases.
利用扫频光学相干断层扫描（SS-OCT）研究不同视网膜疾病中脉络膜海绵状结构的特征。
纳入正常眼、视网膜色素变性（RP）、湿性年龄相关性黄斑变性（wAMD）、急性中心性浆液性脉络膜视网膜病变（CSC）或慢性CSC患者。用SS-OCT评估脉络膜海绵状结构的特征。分析视网膜疾病中脉络膜海绵状结构的患病率以及脉络膜海绵状结构的数量、宽度和深度与脉络膜厚度之间的相关性。
在220名受试者的315只眼中，110只眼（34.9%）发现有脉络膜海绵状结构。脉络膜海绵状结构根据其位置和大小分为两类。I型较小，通常呈分叶状，出现在脉络膜毛细血管层和萨特勒层。II型较大，通常孤立，出现在萨特勒层和哈勒层。正常眼、RP、wAMD、急性CSC或慢性CSC患者中I型的患病率分别为17.4%、19.6%、1.6%、32.8%和85.2%，而II型的患病率分别为0%、0%、21.3%、13.8%和53.7%。II型脉络膜海绵状结构的数量、宽度和厚度与黄斑脉络膜厚度呈正相关。
脉络膜海绵状结构可分为两类。II型脉络膜海绵状结构似乎与厚脉络膜谱系和视网膜色素上皮萎缩性疾病有关。
