Student Wellness and Counselling Centre, UC-5000, Memorial University of Newfoundland, St John's, NL, A1C 5S7.
Student Wellness and Counselling Centre, Memorial University of Newfoundland, St John's, Newfoundland, Canada.
J Clin Psychiatry. 2019 Jul 23;80(4):18r12527. doi: 10.4088/JCP.18r12527.
To estimate the prevalence of anxiety disorders in pregnant and postpartum women and identify predictors accounting for variability across estimates.
An electronic search of PsycINFO and PubMed was conducted from inception until July 2016, without date or language restrictions, and supplemented by articles referenced in the obtained sources. A Boolean search phrase utilized a combination of keywords related to pregnancy, postpartum, prevalence, and specific anxiety disorders.
Articles reporting the prevalence of 1 or more of 8 common anxiety disorders in pregnant or postpartum women were included. A total of 2,613 records were retrieved, with 26 studies ultimately included.
Anxiety disorder prevalence and potential predictor variables (eg, parity) were extracted from each study. A Bayesian multivariate modeling approach estimated the prevalence and between-study heterogeneity of each disorder and the prevalence of having 1 or more anxiety disorder.
Individual disorder prevalence estimates ranged from 1.1% for posttraumatic stress disorder to 4.8% for specific phobia, with the prevalence of having at least 1 or more anxiety disorder estimated to be 20.7% (95% highest density interval [16.7% to 25.4%]). Substantial between-study heterogeneity was observed, suggesting that "true" prevalence varies broadly across samples. There was evidence of a small (3.1%) tendency for pregnant women to be more susceptible to anxiety disorders than postpartum women.
Peripartum anxiety disorders are more prevalent than previously thought, with 1 in 5 women in a typical sample meeting diagnostic criteria for at least 1 disorder. These findings highlight the need for anxiety screening, education, and referral in obstetrics and gynecology settings.
评估孕妇和产后女性焦虑障碍的患病率，并确定导致估计值差异的预测因素。
从开始到 2016 年 7 月，对 PsycINFO 和 PubMed 进行了电子搜索，没有日期或语言限制，并补充了从获得的来源中引用的文章。使用与妊娠、产后、患病率和特定焦虑障碍相关的关键词的布尔搜索短语。
纳入了报告 1 种或多种 8 种常见焦虑障碍在孕妇或产后妇女中患病率的文章。共检索到 2613 条记录，最终有 26 项研究入选。
从每项研究中提取焦虑障碍患病率和潜在预测变量（例如，产次）。贝叶斯多变量建模方法估计了每种障碍的患病率和研究间异质性，以及患有 1 种或多种焦虑障碍的患病率。
个体障碍患病率估计值从创伤后应激障碍的 1.1%到特定恐惧症的 4.8%不等，至少有 1 种或多种焦虑障碍的患病率估计为 20.7%（95%最高密度区间[16.7%至 25.4%]）。观察到研究间存在很大的异质性，表明“真实”患病率在样本之间广泛变化。有证据表明，孕妇比产后妇女更容易患焦虑障碍，这种倾向很小（3.1%）。
围产期焦虑障碍比以前认为的更为普遍，典型样本中有 1/5 的女性符合至少 1 种疾病的诊断标准。这些发现强调了在妇产科环境中进行焦虑筛查、教育和转诊的必要性。
