Suppr超能文献

成人原发性胸段神经母细胞瘤:一例罕见病例报告。

Primary thoracic neuroblastoma in an adult: A rare case report.

作者信息

Tan Yan-Bin, Li Jin-Fan, Li Wen-Shan, Yang Run-Lin

机构信息

Department of Radiology.

Department of Pathology.

出版信息

Medicine (Baltimore). 2019 Jul;98(30):e16564. doi: 10.1097/MD.0000000000016564.

Abstract

RATIONALE

Neuroblastoma is one of the most common malignant tumors in childhood, which mainly occurs in adrenal glands and peripheral sympathetic nerve system. Neuroblastoma occurring in adulthood is rare, and adults with neuroblastoma arising from thorax are exceedingly rare. A case of neuroblastoma that originated from thorax was reported, and was treated by resection operation.

PATIENT CONCERNS

A 46-year-old woman was admitted to our hospital with left side chest pain for 5 days. Laboratory examinations were all normal. Chest computerized tomogram (CT) showed a lesion with clear boundary that was located at the left dorsal pleura. The nature of the mass was heterogeneous, showing slight heterogeneous enhancement after contrast and there was no obvious necrosis.

DIAGNOSES

Based on the morphologic and immunohistochemical features, the tumor diagnosis was favorable for neuroblastoma.

INTERVENTIONS

A resection operation was carried out.

OUTCOMES

Three years postoperative, no sign of recurrence or metastasis has been observed.

LESSONS

Primary neuroblastoma in adulthood is rare and has poor prognosis. Resection can be an important treatment option, and combining with other methods like chemotherapy, stem cell transplantation, the survival rate may be improved.

摘要

理论依据

神经母细胞瘤是儿童期最常见的恶性肿瘤之一,主要发生于肾上腺和周围交感神经系统。成人神经母细胞瘤罕见,起源于胸部的成人神经母细胞瘤极为罕见。本文报道1例起源于胸部的神经母细胞瘤,并经手术切除治疗。

患者情况

一名46岁女性因左侧胸痛5天入院。实验室检查均正常。胸部计算机断层扫描(CT)显示左背侧胸膜有一边界清晰的病变。肿块性质不均一,增强扫描后呈轻度不均一强化,无明显坏死。

诊断

根据形态学和免疫组化特征,肿瘤诊断为神经母细胞瘤。

干预措施

行手术切除。

结果

术后3年,未观察到复发或转移迹象。

经验教训

成人原发性神经母细胞瘤罕见,预后较差。手术切除是重要的治疗选择,联合化疗、干细胞移植等其他方法,可能提高生存率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f7e/6709284/46490b132de6/medi-98-e16564-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验