• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
MIC and fungicidal activity of terbinafine against clinical isolates of Aspergillus spp.特比萘芬对曲霉属临床分离株的最低抑菌浓度及杀菌活性
Antimicrob Agents Chemother. 1988 May;32(5):780-1. doi: 10.1128/AAC.32.5.780.
2
Synergistic interaction of terbinafine with triazoles or amphotericin B against Aspergillus species.特比萘芬与三唑类药物或两性霉素B对曲霉菌的协同相互作用。
Med Mycol. 2001 Feb;39(1):91-5. doi: 10.1080/mmy.39.1.91.95.
3
[The effect of propyl gallate on the activity of various antifungal drugs against filamentous fungi in vitro].[棓丙酯对多种抗真菌药物体外抗丝状真菌活性的影响]
Zhonghua Yan Ke Za Zhi. 2006 Apr;42(4):309-12.
4
[In vitro sensitivity of Aspergillus to terbinafine: comparative study on amphotericin B, 5-fluorocytosine and ketoconazole].[曲霉菌对特比萘芬的体外敏感性：两性霉素B、5-氟胞嘧啶和酮康唑的比较研究]
Pathol Biol (Paris). 1988 Feb;36(2):139-43.
5
In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp.特比萘芬与伊曲康唑、氟康唑、两性霉素B及5-氟胞嘧啶在体外对曲霉属真菌的相互作用
J Antimicrob Chemother. 2002 Aug;50(2):189-94. doi: 10.1093/jac/dkf111.
6
Discrepancies between MIC and MLC values of amphotericin B against isolates of Aspergillus species.两性霉素B对曲霉菌分离株的最低抑菌浓度（MIC）和最低杀菌浓度（MLC）值之间的差异。
Mycopathologia. 1994 Dec;128(3):129-33. doi: 10.1007/BF01138472.
7
In-vitro activities of terbinafine, itraconazole and amphotericin B against Aspergillus and Cladosporium species.特比萘芬、伊曲康唑和两性霉素B对曲霉菌和枝孢菌属的体外活性。
J Chemother. 2002 Dec;14(6):562-7. doi: 10.1179/joc.2002.14.6.562.
8
In-vitro activity of the new triazole D0870 compared with amphotericin B and itraconazole against Aspergillus spp.新型三唑类药物D0870与两性霉素B及伊曲康唑相比，对曲霉属真菌的体外活性
J Antimicrob Chemother. 1993 Dec;32(6):831-6. doi: 10.1093/jac/32.6.831.
9
In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B.特比萘芬对曲霉菌属的体外活性与伊曲康唑和两性霉素B的比较。
Antimicrob Agents Chemother. 2001 Jun;45(6):1882-5. doi: 10.1128/AAC.45.6.1882-1885.2001.
10
In vitro activities of amphotericin B in combination with four antifungal agents and rifampin against Aspergillus spp.两性霉素B联合四种抗真菌药物及利福平对曲霉属真菌的体外活性
Antimicrob Agents Chemother. 1984 May;25(5):560-2. doi: 10.1128/AAC.25.5.560.

引用本文的文献

1
Molecular Identification of Species, Antifungal Susceptibility, and Phenotypic Identification of Azole-Resistant Mutations in Cyp51A Gene Isolated from Xinjiang.新疆分离株的菌种分子鉴定、抗真菌药敏性及Cyp51A基因唑类耐药突变的表型鉴定
Infect Drug Resist. 2025 Apr 2;18:1699-1711. doi: 10.2147/IDR.S496489. eCollection 2025.
2
Terbinafine as a successful treatment in primary cutaneous aspergillosis.特比萘芬作为原发性皮肤曲霉病的一种成功治疗方法。
An Bras Dermatol. 2024 Jul-Aug;99(4):647-649. doi: 10.1016/j.abd.2023.07.011. Epub 2024 Apr 22.
3
Identification and in vitro antifungal susceptibility of causative agents of onychomycosis due to Aspergillus species in Mashhad, Iran.伊朗马什哈德地区由曲霉属引起的甲真菌病的病原体鉴定及体外抗真菌药敏试验。
Sci Rep. 2021 Mar 24;11(1):6808. doi: 10.1038/s41598-021-86038-z.
4
Molecular Identification and Antifungal Susceptibility of Yeasts and Molds Isolated from Patients with Otomycosis.从耳真菌病患者中分离出的酵母和霉菌的分子鉴定及抗真菌药敏试验。
Mycopathologia. 2021 May;186(2):245-257. doi: 10.1007/s11046-021-00537-1. Epub 2021 Mar 15.
5
Molecular identification and antifungal susceptibilities of black Aspergillus isolates from otomycosis cases in Hungary.匈牙利耳真菌病病例中黑色曲霉菌的分子鉴定及抗真菌药敏性
Mycopathologia. 2012 Aug;174(2):143-7. doi: 10.1007/s11046-012-9529-8. Epub 2012 Feb 23.
6
Update on terbinafine with a focus on dermatophytoses.特比萘芬更新：重点关注皮肤癣菌病。
Clin Cosmet Investig Dermatol. 2009 Apr 21;2:49-63. doi: 10.2147/ccid.s3690.
7
Fungal cell wall septation and cytokinesis are inhibited by bleomycins.博来霉素可抑制真菌细胞壁的分隔和胞质分裂。
Antimicrob Agents Chemother. 2003 Oct;47(10):3281-9. doi: 10.1128/AAC.47.10.3281-3289.2003.
8
In vitro activities of terbinafine against Aspergillus species in comparison with those of itraconazole and amphotericin B.特比萘芬对曲霉菌属的体外活性与伊曲康唑和两性霉素B的比较。
Antimicrob Agents Chemother. 2001 Jun;45(6):1882-5. doi: 10.1128/AAC.45.6.1882-1885.2001.
9
Invasive aspergillosis caused by Aspergillus ustus: case report and review.由ustus曲霉引起的侵袭性曲霉病：病例报告及文献复习
J Clin Microbiol. 1999 May;37(5):1606-9. doi: 10.1128/JCM.37.5.1606-1609.1999.
10
Antifungal agents in the 1990s. Current status and future developments.20世纪90年代的抗真菌药物。现状与未来发展。
Drugs. 1997 Apr;53(4):539-49. doi: 10.2165/00003495-199753040-00001.

本文引用的文献

1
Synthesis and antifungal activity of (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphtha lenemethanamine (SF 86-327) and related allylamine derivatives with enhanced oral activity.（E）-N-（6,6-二甲基-2-庚烯-4-炔基）-N-甲基-1-萘甲胺（SF 86-327）及具有增强口服活性的相关烯丙胺衍生物的合成与抗真菌活性
J Med Chem. 1984 Dec;27(12):1539-43. doi: 10.1021/jm00378a003.
2
Effect of the antimycotic drug naftifine on growth of and sterol biosynthesis in Candida albicans.抗真菌药物萘替芬对白色念珠菌生长及甾醇生物合成的影响。
Antimicrob Agents Chemother. 1984 Apr;25(4):483-7. doi: 10.1128/AAC.25.4.483.
3
Specific inhibition of fungal sterol biosynthesis by SF 86-327, a new allylamine antimycotic agent.新型烯丙胺类抗真菌剂SF 86-327对真菌甾醇生物合成的特异性抑制作用。
Antimicrob Agents Chemother. 1985 Feb;27(2):252-6. doi: 10.1128/AAC.27.2.252.
4
Inhibition of squalene epoxidase by allylamine antimycotic compounds. A comparative study of the fungal and mammalian enzymes.烯丙胺抗真菌化合物对角鲨烯环氧酶的抑制作用。真菌和哺乳动物酶的比较研究。
Biochem J. 1985 Sep 15;230(3):765-70. doi: 10.1042/bj2300765.
5
Antifungal activity of the allylamine derivative terbinafine in vitro.烯丙胺衍生物特比萘芬的体外抗真菌活性。
Antimicrob Agents Chemother. 1987 Sep;31(9):1365-8. doi: 10.1128/AAC.31.9.1365.
6
In-vitro studies with SF 86-327, a new orally active allylamine derivative.使用新型口服活性烯丙胺衍生物SF 86 - 327进行的体外研究。
Sabouraudia. 1985 Apr;23(2):125-32. doi: 10.1080/00362178585380201.

特比萘芬对曲霉属临床分离株的最低抑菌浓度及杀菌活性

MIC and fungicidal activity of terbinafine against clinical isolates of Aspergillus spp.

作者信息

Schmitt H J, Bernard E M, Andrade J, Edwards F, Schmitt B, Armstrong D

机构信息

Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.

出版信息

Antimicrob Agents Chemother. 1988 May;32(5):780-1. doi: 10.1128/AAC.32.5.780.

DOI:10.1128/AAC.32.5.780
PMID:3134851
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172275/
Abstract

Terbinafine and amphotericin B MICs for 90% of strains tested were 1.6 and 0.4 micrograms/ml against Aspergillus fumigatus (16 strains), 0.8 and 3.2 micrograms/ml against Aspergillus flavus (10 strains), and 0.4 and 1.6 micrograms/ml against Aspergillus niger (10 strains), respectively. For all species tested, the minimal inhibitory and fungicidal concentrations for 90% of strains of both drugs were identical and the inoculum size did not have a major effect on the results.

摘要

对于90%的受试菌株，特比萘芬和两性霉素B对烟曲霉（16株）的最低抑菌浓度分别为1.6微克/毫升和0.4微克/毫升，对黄曲霉（10株）的最低抑菌浓度分别为0.8微克/毫升和3.2微克/毫升，对黑曲霉（10株）的最低抑菌浓度分别为0.4微克/毫升和1.6微克/毫升。对于所有受试菌种，两种药物对90%菌株的最低抑菌浓度和最低杀菌浓度相同，接种量对结果没有重大影响。