Verweij P E, van den Bergh M F, Rath P M, de Pauw B E, Voss A, Meis J F
Departments of Medical Microbiology, University Hospital Nijmegen, Nijmegen, The Netherlands.
J Clin Microbiol. 1999 May;37(5):1606-9. doi: 10.1128/JCM.37.5.1606-1609.1999.
A case of invasive pulmonary aspergillosis in an allogeneic bone marrow transplant recipient caused by Aspergillus ustus is presented. A. ustus was also recovered from the hospital environment, which may indicate that the infection was nosocomially acquired. A literature review revealed seven cases of invasive infections caused by A. ustus, and three of these were primarily cutaneous infections. In vitro susceptibility testing of 12 A. ustus isolates showed that amphotericin B and terbinafine had fungicidal activity and that itraconazole and voriconazole had fungistatic activity.
本文报告了1例由ustus曲霉引起的异基因骨髓移植受者侵袭性肺曲霉病病例。ustus曲霉也从医院环境中分离得到,这可能表明该感染是医院获得性感染。文献回顾显示有7例由ustus曲霉引起的侵袭性感染病例,其中3例主要为皮肤感染。对12株ustus曲霉分离株进行的体外药敏试验表明,两性霉素B和特比萘芬具有杀菌活性,伊曲康唑和伏立康唑具有抑菌活性。