Browett P J, Varcoe A R, Fraser A G, Ellis-Pegler R B
Department of Hematology, Auckland Hospital, New Zealand.
Aust N Z J Med. 1988 Feb;18(1):79-80. doi: 10.1111/j.1445-5994.1988.tb02250.x.
A 43-year-old Polynesian presented with fever, abnormal liver function tests, bilateral pulmonary infiltrates, and a progressive neutropenia and thrombocytopenia. Bone marrow examination showed extensive and striking hemophagocytosis which raised the diagnosis of malignant histiocytosis. Mycobacterium tuberculosis was subsequently cultured from both urine and bone marrow. Hemophagocytosis is now a recognised association of several infections and we draw attention to this finding, particularly as the confident exclusion of malignancy can be very difficult and management is obviously very different.
一名43岁的波利尼西亚人出现发热、肝功能检查异常、双侧肺部浸润以及进行性中性粒细胞减少和血小板减少。骨髓检查显示广泛且显著的噬血细胞增多，这提示了恶性组织细胞增多症的诊断。随后从尿液和骨髓中培养出结核分枝杆菌。噬血细胞增多目前被认为是几种感染的相关表现，我们提请注意这一发现，特别是因为要确切排除恶性肿瘤非常困难，且治疗方法明显不同。
