位点可编程转座：为 CRISPR-Cas 系统转换范式。

Site-Programmable Transposition: Shifting the Paradigm for CRISPR-Cas Systems.

机构信息

Department of Bioengineering, Stanford University, Stanford, CA, USA.

Department of Bioengineering, Stanford University, Stanford, CA, USA; Department of Chemical and Systems Biology, Stanford University, Stanford, CA, USA; ChEM-H, Stanford University, Stanford, CA, USA.

出版信息

Mol Cell. 2019 Jul 25;75(2):206-208. doi: 10.1016/j.molcel.2019.07.004.

DOI:10.1016/j.molcel.2019.07.004

PMID:31348878

Abstract

Discoveries by Klompe et al. (2019) and Strecker et al. (2019) elucidate distinct CRISPR-Cas mechanisms for site-specific programmable transposition in prokaryotic organisms.

摘要

克洛姆普等人（2019 年）和施特雷克尔等人（2019 年）的发现阐明了原核生物中特定 CRISPR-Cas 机制用于位点特异性可编程转座的不同机制。