Duke Office of Scientific Integrity - Conflict of Interest, Duke University , Durham , NC , USA.
Department of Biostatistics and Bioinformatics, Duke University , Durham , NC , USA.
Account Res. 2019 Aug;26(6):397-403. doi: 10.1080/08989621.2019.1636652. Epub 2019 Jul 26.
We consider the question of why (primarily) and how (secondarily) to perform scientific oversight of research performed by investigators with a financial conflict of interest (COI). One way to frame the trade-off of having investigators with financial COI participate in research is through a decision rule: "". A key component of COI management is the demonstration that the underlying science is sufficiently rigorous and transparent, and in turn, a scientific oversight plan is a key element of that demonstration. Scientific oversight plans should be proactively generated, by individuals (i.e., scientific reviewers) who are independent and expert, and they should assess the rigor and transparency of the research, in a fashion which is fair and efficient. COI: conflict of interest; SOP: scientific oversight plan.
我们探讨了对存在财务利益冲突（COI）的研究者所进行的研究进行科学监督的原因（主要）和方式（其次）。通过决策规则来框定有财务 COI 的研究者参与研究的利弊权衡是一种方法：“”。COI 管理的一个关键组成部分是证明基础科学足够严谨和透明，而科学监督计划是证明这一点的关键要素。科学监督计划应由独立且专业的个人（即科学审查员）主动制定，并且应该以公平有效的方式评估研究的严谨性和透明度。COI：利益冲突；SOP：科学监督计划。
