Jaszkul Katrina M, Kemp Austin, Alghanim Khalifa, Letourneau Sasha, Kim Stephanie, Simpson Andrew
School of Medicine, Queens University, Kingston, ON, Canada.
Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.
Plast Surg (Oakv). 2025 May;33(2):224-229. doi: 10.1177/22925503231217512. Epub 2023 Nov 30.
Cryolipolysis has emerged as a nonsurgical fat reduction alternative to liposuction. Industry payments may impact how physician authors view medical devices in the literature. Under-reporting financial conflicts of interest has raised concerns about full transparency between industry and physicians. We aim to determine the impact industry payments to physicians have on the cryolipolysis literature and whether there is under-reporting of financial conflicts of interest in the literature. We collated all articles that cite the pivotal trial in the Food and Drug Administration approval of a cryolipolysis device. Articles were read independently and coded as favourable or neutral. A separate researcher screened the Centers for Medicare & Medicaid Services Open Payments database for direct or in-kind payments and recorded financial conflicts of interest. A total of 19 articles met the inclusion criteria. This included 37 unique authors across multiple specialties. Eighteen (95%) published articles had at least one author who received industry payment. Payments totalled $1,476,564.16. Twelve (63%) articles were positive, and 7 (37%) neutral. Of the 31 authors who received payments, 11 (35%) did not report a conflict of interest. The majority of industry payments assessed were for consulting fees, which totalled $980,334.86 (66.4%). We found the majority of published opinions on cryolipolysis from the United States were written by physicians who received industry payments. We also found financial conflicts of interest around cryolipolysis devices are under-reported in the literature.
冷冻溶脂术已成为一种替代抽脂术的非手术减脂方法。行业支付可能会影响医学文献中医生作者对医疗设备的看法。未充分披露利益冲突引发了人们对行业与医生之间全面透明度的担忧。我们旨在确定行业向医生支付款项对冷冻溶脂术文献的影响，以及该文献中是否存在利益冲突披露不足的情况。我们整理了所有引用美国食品药品监督管理局批准一款冷冻溶脂设备的关键试验的文章。文章由独立人员阅读并编码为支持或中立。另一位研究人员在医疗保险和医疗补助服务中心公开支付数据库中筛选直接或实物支付情况，并记录利益冲突。共有19篇文章符合纳入标准。这包括来自多个专业的37位不同作者。18篇（95%）已发表文章至少有一位作者接受了行业支付。支付总额为1,476,564.16美元。12篇（63%）文章为支持性的，7篇（37%）为中立性的。在接受支付的31位作者中，11位（35%）未报告利益冲突。评估的行业支付大部分是咨询费，总计980,334.86美元（66.4%）。我们发现美国关于冷冻溶脂术的大多数已发表观点是由接受行业支付的医生撰写的。我们还发现冷冻溶脂设备相关的利益冲突在文献中披露不足。
