Development. 2019 Jul 26;146(14):dev182733. doi: 10.1242/dev.182733.
Most bones in the vertebrate skeleton are made in the same way - endochondrial ossification - yet they display a variety of shapes and sizes. The question of how these unique bone morphologies, including the superstructures that protrude from their surfaces, arise during development is still unclear, and the subject of a new paper in Development We caught up with first author Shai Eyal and his supervisor Elazar Zelzer, Professor in the Department of Molecular Genetics at the Weizmann Institute of Science in Rehovot, Israel, to find out more about the story.
大多数脊椎动物骨骼中的骨头都是以同样的方式形成的——软骨内骨化——但它们呈现出各种形状和大小。在发育过程中,这些独特的骨骼形态(包括从表面突出的超结构)是如何产生的,这个问题仍不清楚,也是以色列雷霍沃特魏茨曼科学研究所分子遗传学系教授 Elazar Zelzer 的一篇新论文的主题。我们联系了第一作者 Shai Eyal 和他的导师,以了解更多关于这个故事的信息。