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中国山东成年人 24 小时尿钠排泄与血压的关系。

Relationship between 24-hour urinary sodium excretion and blood pressure in the adult population in Shandong, China.

机构信息

Department of Cardiology, Shandong Provincial Hospital Affiliated to Shandong University, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Ji'nan, China.

Department of Heart Center, Hypertensive Laboratory, Peking University People's Hospital, Beijing, China.

出版信息

J Clin Hypertens (Greenwich). 2019 Sep;21(9):1370-1376. doi: 10.1111/jch.13644. Epub 2019 Jul 26.

DOI:10.1111/jch.13644
PMID:31350809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6771517/
Abstract

The main objective of this study was to determine baseline salt intake levels in a sample of the adult population of Shandong province and to establish the relationship between urinary sodium excretion and blood pressure. A total of 512 participants were recruited, and all the participants provided complete 24-hour urine collections. Physical assessment and socioeconomic status of participants were collected at the same time. The mean 24-hour urinary sodium excretion of all subjects was 228.0 ± 127.5 mmol/24 hours. Estimated salt intake was higher in obese subjects (17.6 ± 8.8 g/d) compared with overweight subjects (15.6 ± 8.0 g/d) and those with a normal BMI (13.9 ± 6.8 g/d). Likewise, urinary sodium excretion of hypertensive participants was dramatically higher than that of non-hypertensive ones, the equivalent of 18.2 ± 9.1 g/d vs 13.3 ± 6.8 g/d. Urinary sodium was significantly associated with SBP (β = 1.08, P = .018) after adjustment for potential confounders. In summary, we found significantly high levels of salt intake in Shandong Province, particularly in obese and hypertension subjects. It is quite important to improve public education about reducing salt intake to control blood pressure among Shandong people.

摘要

本研究的主要目的是确定山东省部分成年人群的基础盐摄入量,并确定尿钠排泄与血压之间的关系。共招募了 512 名参与者,所有参与者均提供了完整的 24 小时尿液收集。同时收集了参与者的体格评估和社会经济状况。所有受试者的平均 24 小时尿钠排泄量为 228.0±127.5mmol/24 小时。与超重受试者(15.6±8.0g/d)和体重正常受试者(13.9±6.8g/d)相比,肥胖受试者的估计盐摄入量更高(17.6±8.8g/d)。同样,高血压参与者的尿钠排泄量明显高于非高血压参与者,分别为 18.2±9.1g/d 和 13.3±6.8g/d。在调整了潜在混杂因素后,尿钠与 SBP 呈显著正相关(β=1.08,P=.018)。总之,我们发现山东省的盐摄入量明显较高,尤其是在肥胖和高血压人群中。提高公众关于减少盐摄入量以控制山东人群血压的教育水平非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5e/8030560/9b556fd00242/JCH-21-1370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5e/8030560/65b085ce8148/JCH-21-1370-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5e/8030560/9b556fd00242/JCH-21-1370-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5e/8030560/65b085ce8148/JCH-21-1370-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5e/8030560/9b556fd00242/JCH-21-1370-g001.jpg

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High salt intake: independent risk factor for obesity?高盐摄入:肥胖的独立危险因素?
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