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通过7至11岁西班牙受试者24小时尿钠排泄量评估盐摄入量

Estimation of salt intake assessed by urinary excretion of sodium over 24 h in Spanish subjects aged 7-11 years.

作者信息

Aparicio A, Rodríguez-Rodríguez E, Cuadrado-Soto E, Navia B, López-Sobaler A M, Ortega R M

机构信息

Departamento de Nutrición Y Bromatología I (Nutrición), Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

UCM Research Group: VALORNUT-920030, Madrid, Spain.

出版信息

Eur J Nutr. 2017 Feb;56(1):171-178. doi: 10.1007/s00394-015-1067-y. Epub 2015 Oct 19.

Abstract

PURPOSE

High intake of salt is associated with early development of cardiovascular risk factors (e.g., hypertension, obesity). In "developed" countries, individuals frequently exceed dietary recommendations for salt intake. Taking into account the limited data on sodium intake by 24-h excretion in urine in schoolchildren, we wished to determine baseline salt intake in Spanish subjects aged 7-11 years.

METHODS

The present study was an observational study involving 205 schoolchildren (109 boys and 96 girls) selected from various Spanish provinces. Sodium intake was ascertained by measuring sodium excretion in urine over 24 h. Creatinine was used to validate completeness of urine collections. The correlation between fat-free mass determined by anthropometry and that determined via urinary excretion of creatinine was calculated (r = 0.651; p < 0.001).

RESULTS

Mean 24-h urinary excretion of sodium was 132.7 ± 51.4 mmol/24 h (salt equivalent: 7.8 ± 3.1 g/day). Hence, 84.5 % of subjects aged ≤10 years had intakes of >4 g salt/day, and 66.7 % of those aged >10 years had intakes of >5 g salt/day. Urinary excretion of sodium was correlated with systolic blood pressure and diastolic blood pressure (r = 0.1574 and r = 0.1400, respectively). Logistic regression analyses, adjusted by sex, showed that a high body mass index (odds ratio = 1.159; 95 % CI 1.041-1.290; p < 0.05) was associated with an increased likelihood of high urinary excretion of sodium.

CONCLUSIONS

Sodium intake, as estimated by 24-h urinary excretion, was (on average) higher than recommended. Reducing the sodium content children's diet is a sound policy to reduce cardiovascular risk.

摘要

目的

高盐摄入与心血管危险因素(如高血压、肥胖)的早期出现有关。在“发达国家”,个体经常超过盐摄入的膳食建议量。鉴于关于学龄儿童24小时尿钠排泄量的钠摄入量数据有限,我们希望确定7至11岁西班牙受试者的基线盐摄入量。

方法

本研究为一项观察性研究,涉及从西班牙不同省份选取的205名学龄儿童(109名男孩和96名女孩)。通过测量24小时尿钠排泄量来确定钠摄入量。使用肌酐来验证尿液收集的完整性。计算通过人体测量法测定的去脂体重与通过肌酐尿排泄量测定的去脂体重之间的相关性(r = 0.651;p < 0.001)。

结果

24小时尿钠平均排泄量为132.7 ± 51.4 mmol/24小时(盐当量:7.8 ± 3.1 g/天)。因此,≤10岁的受试者中有84.5%的盐摄入量>4 g/天,>10岁的受试者中有66.7%的盐摄入量>5 g/天。尿钠排泄量与收缩压和舒张压相关(分别为r = 0.1574和r = 0.1400)。经性别调整的逻辑回归分析表明,高体重指数(优势比 = 1.159;95%置信区间1.041 - 1.290;p < 0.05)与高尿钠排泄的可能性增加相关。

结论

通过24小时尿排泄量估算的钠摄入量(平均)高于推荐量。降低儿童饮食中的钠含量是降低心血管风险的合理策略。

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