Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin, China (mainland).
Department of Orthopedic Surgery, Affiliated Hospital of Logistics, University of Chinese Armed Police Force, Tianjin, China (mainland).
Med Sci Monit. 2019 Jul 27;25:5580-5588. doi: 10.12659/MSM.914182.
BACKGROUND The factors associated with osteoporosis are poorly understood in the Chinese population. This study aimed to examine the factors associated with osteoporosis and with fractures in a Chinese elderly population. MATERIAL AND METHODS This was a cross-sectional study of elderly people living in Tianjin between 2012 and 2014. Bone mineral density was measured by dual X-ray absorptiometry. The subjects completed a questionnaire about lifestyle habits, personal and family medical history, calcium intake, and exercising. Data were gathered on occurrence of fracture at 5 years or August 2018, whichever occurred first. RESULTS There were 298 individuals with osteoporosis (18.5% male, median age 67 years) and 397 without (46.3% male, median age 62 years). Male sex (OR=0.051, 95% CI: 0.021-0.126), age (OR=1.049, 95% CI: 1.099-1.202), being divorced/widowed (OR=2.445, 95% CI: 1.219-4.904), digestive ulcer history (OR=3.805, 95% CI: 1.539-9.405), family history of hunchback (OR=2.659, 95% CI: 1.145-6.175), family history of osteoarthropathy (OR=4.222, 95% CI: 2.128-8.375), fracture history (OR=2.138, 95% CI: 1.307-3.496), drinking green tea (OR=0.352, 95% CI: 0.217-0.574), and exercising (OR=0.303, 95% CI: 0.193-0.475) were independently associated with osteoporosis. Digestive ulcer history (OR=3.183, 95% CI: 1.178-8.5992), exercising (OR=0.354, 95% CI: 0.139-0.903), and taking calcium supplements during follow-up (OR=0.262, 95% CI: 0.112-0.611) were independently associated with fractures in patients with osteoporosis. CONCLUSIONS Female sex, age, marital status, history of digestive ulcer and fracture, and family history of hunchback and osteoarthropathy are associated with osteoporosis among elderly subjects, while drinking green tea and exercising are inversely associated. Among the patients with osteoporosis, a history of digestive ulcer is associated with fractures, while exercising and taking calcium supplements are inversely associated.
骨质疏松症的相关因素在中国人中了解甚少。本研究旨在探讨中国老年人群中与骨质疏松症和骨折相关的因素。
这是一项 2012 年至 2014 年期间在天津居住的老年人的横断面研究。通过双能 X 线吸收法测量骨矿物质密度。受试者完成了一份关于生活习惯、个人和家族病史、钙摄入量和运动的问卷。收集了 5 年内或 2018 年 8 月(以先发生者为准)骨折的发生数据。
共有 298 名骨质疏松症患者(18.5%为男性,中位年龄 67 岁)和 397 名非骨质疏松症患者(46.3%为男性,中位年龄 62 岁)。男性(OR=0.051,95%CI:0.021-0.126)、年龄(OR=1.049,95%CI:1.099-1.202)、离异/丧偶(OR=2.445,95%CI:1.219-4.904)、消化性溃疡病史(OR=3.805,95%CI:1.539-9.405)、驼背家族史(OR=2.659,95%CI:1.145-6.175)、骨关节炎家族史(OR=4.222,95%CI:2.128-8.375)、骨折病史(OR=2.138,95%CI:1.307-3.496)、饮用绿茶(OR=0.352,95%CI:0.217-0.574)和运动(OR=0.303,95%CI:0.193-0.475)与骨质疏松症独立相关。消化性溃疡病史(OR=3.183,95%CI:1.178-8.5992)、运动(OR=0.354,95%CI:0.139-0.903)和随访期间补钙(OR=0.262,95%CI:0.112-0.611)与骨质疏松症患者的骨折独立相关。
女性、年龄、婚姻状况、消化性溃疡和骨折病史以及驼背和骨关节炎家族史与老年人群的骨质疏松症相关,而饮用绿茶和运动与之相反。在骨质疏松症患者中,消化性溃疡病史与骨折相关,而运动和补钙与之相反。