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经口内镜肌切开术与腹腔镜 Heller 肌切开术的成本比较和短期临床结果。

Comparison of costs and short-term clinical outcomes of per-oral endoscopic myotomy and laparoscopic Heller myotomy.

机构信息

Department of General, Thoracic and Vascular Surgery, Virginia Mason Medical Center, Seattle, WA, 98111, United States.

Department of Analytics, Virginia Mason Medical Center, Seattle, WA, 98111, United States.

出版信息

Am J Surg. 2019 Oct;218(4):706-711. doi: 10.1016/j.amjsurg.2019.07.026. Epub 2019 Jul 18.

Abstract

OBJECTIVE

Per-Oral Endoscopic Myotomy (POEM) has seen increasing application and comparisons to laparoscopic Heller myotomy (LHM). The aim of the present study was to compare perioperative and short-term outcomes, and costs between the two procedures at a single institution.

METHODS

Fifty-one consecutive patients documented in a prospective IRB approved database from January 2014 to December 2017 were included. Perioperative data, pre-operative and 3-month postoperative Eckardt Scores, and cost data were compared.

RESULTS

Median hospital stay was comparable between POEM and LHM (1 day each). Complications were minor (Clavien-Dindo 1, 2) and rare in both groups. Median Eckardt scores improved significantly after POEM (5 to 0) and LHM (5 to 0). Normalized median costs were comparable: 14 201 USD (POEM) vs. 13 328 USD (LHM) p = 0.45.

CONCLUSIONS

POEM demonstrates comparable clinical outcomes and costs to LHM. Long-term issues related to GERD require ongoing assessment in POEM patients.

SUMMARY

In patients with achalasia, extended myotomy of the lower esophageal sphincter offers excellent palliation of symptoms. In the last decades, laparoscopic Heller myotomy (LHM) has been the gold standard. Over the past decade, per-oral endoscopic myotomy (POEM) has seen wide application in specialized centers worldwide. In our patient cohort, we demonstrate, that POEM can be introduced with similar outcomes and costs compared to LHM.

摘要

目的

经口内镜下肌切开术(POEM)的应用越来越广泛,并与腹腔镜 Heller 肌切开术(LHM)进行了比较。本研究旨在比较单一机构两种手术的围手术期和短期结果及成本。

方法

回顾性分析 2014 年 1 月至 2017 年 12 月在一家机构接受治疗的 51 例连续患者的前瞻性 IRB 批准数据库,比较围手术期数据、术前和术后 3 个月 Eckardt 评分以及成本数据。

结果

POEM 和 LHM 的中位住院时间相似(均为 1 天)。两组并发症均轻微(Clavien-Dindo 1 级、2 级)且罕见。POEM 和 LHM 后 Eckardt 评分均显著改善(5 分降至 0 分)。标准化中位成本相当:POEM 为 14201 美元,LHM 为 13328 美元(p=0.45)。

结论

POEM 与 LHM 的临床结果和成本相当。与 GERD 相关的长期问题需要对 POEM 患者进行持续评估。

总结

在贲门失弛缓症患者中,对食管下括约肌进行广泛肌切开术可显著缓解症状。在过去几十年中,腹腔镜 Heller 肌切开术(LHM)一直是金标准。在过去十年中,经口内镜下肌切开术(POEM)已在全球多个专业中心广泛应用。在我们的患者队列中,我们证明与 LHM 相比,POEM 可具有相似的结果和成本。

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