Lien Kuang-Hsu, Young Chi-Kuang, Chin Shy-Chyi, Liao Chun-Ta, Huang Shiang-Fu
1 Department of Otolaryngology & Head and Neck Surgery, Chang Gung Memorial Hospital, Linkou, Taiwan.
2 School of Medicine, Chang Gung University, Taoyuan, Taiwan.
J Int Med Res. 2019 Aug;47(8):4004-4013. doi: 10.1177/0300060519862659. Epub 2019 Jul 29.
Primary parapharyngeal space (PPS) tumors are one of the most challenging head and neck tumors to diagnose and treat. We analyzed our experience in patients with PPS tumors who were treated in our hospital over 13 years.
We retrospectively reviewed 16 patients with PPS tumors between 2006 and 2018. The study included clinical symptoms, histological types, surgical approaches, adjuvant therapies, postoperative complications, and prognosis.
The mean age of the patients was 49.63 ± 17.03 years. A palpable neck mass (56.3%) was the most common symptom. In our series, 78.6% of the tumors were benign, and of these, schwannomas were the most common (6/14, 42.9%). Three surgical approaches were used in our patients, including transmandibular (57.1%), transcervical (21.4%) and transparotid (21.4%) approaches. Few complications were reported, including hoarseness and numbness. Adjuvant therapy was administered depending on pathological parameters of the tumors. No recurrence was observed during a mean follow-up of 60.6 months in patients with malignant tumors.
Radiological studies of PPS tumors are essential for diagnosis and surgical planning. Excision of PPS tumors using appropriate surgical approaches provides good outcomes.
原发性咽旁间隙（PPS）肿瘤是最难诊断和治疗的头颈部肿瘤之一。我们分析了13年来在我院接受治疗的PPS肿瘤患者的经验。
我们回顾性分析了2006年至2018年间16例PPS肿瘤患者。该研究包括临床症状、组织学类型、手术方式、辅助治疗、术后并发症及预后。
患者的平均年龄为49.63±17.03岁。可触及颈部肿块（56.3%）是最常见的症状。在我们的系列研究中，78.6%的肿瘤为良性，其中神经鞘瘤最为常见（6/14，42.9%）。我们的患者采用了三种手术方式，包括经下颌骨（57.1%）、经颈部（21.4%）和经腮腺（21.4%）入路。报告的并发症较少，包括声音嘶哑和麻木。根据肿瘤的病理参数给予辅助治疗。恶性肿瘤患者平均随访60.6个月未观察到复发。
PPS肿瘤的影像学检查对诊断和手术规划至关重要。采用适当的手术方式切除PPS肿瘤可取得良好疗效。
