Ughasoro Maduka Donatus, Madu Anazoeze Jude, Kela-Eke Iheoma Clara
Department of Paediatrics, University of Nigeria, Enugu Campus, Enugu, Nigeria.
Department of Haematology, University of Nigeria, Enugu Campus, Enugu, Nigeria.
Int J Pediatr. 2019 Jul 1;2019:3863070. doi: 10.1155/2019/3863070. eCollection 2019.
Anaemia in children has high mortality. We present the results of assessment of the accuracy of Haemoglobin Colour Scale in identifying anaemia compared with HemoCue assay.
The presence of anaemia in 524 children from four communities was screened using the Haemoglobin Colour Scale (HCS) and HemoCue assay. Independent healthcare providers that estimated the haemoglobin level using Hb-301 haemoglobinometer were different from those that read the colour scale. The sensitivity, specificity, positive predictive value, and negative predictive value were estimated.
Of the 524 children surveyed, 44.5% (233/524), 50% (262/524), and 32.2% (168/524) were found to be anaemic using the HemoCue, HCS (= 0.25), and clinical pallor (=0.03) respectively. Using the HemoCue as standard, the sensitivity of the HCS and clinical pallor was 89.1% and 72.1%, respectively, and specificity 90.2% and 84.6%, respectively. 74.7 % of the colour scale result was within the 1.0g/dl of the HemoCue reading and 23 % was within 2.0g/dl.
The HCS can improve the ability to detect anaemia especially where the use of the HemoCue is not feasible as in the resource poor countries. However, every case of anaemia requires further investigation to determine the underlying causes.
儿童贫血具有较高的死亡率。我们展示了与HemoCue检测法相比，血红蛋白比色卡识别贫血准确性的评估结果。
使用血红蛋白比色卡（HCS）和HemoCue检测法对来自四个社区的524名儿童进行贫血筛查。使用Hb - 301血红蛋白仪估计血红蛋白水平的独立医疗服务提供者与读取比色卡的人员不同。估计了灵敏度、特异度、阳性预测值和阴性预测值。
在接受调查的524名儿童中，使用HemoCue检测法、HCS（= 0.25）和临床面色苍白（= 0.03）分别发现44.5%（233/524）、50%（262/524）和32.2%（168/524）的儿童患有贫血。以HemoCue检测法为标准，HCS和临床面色苍白的灵敏度分别为89.1%和72.1%，特异度分别为90.2%和84.6%。比色卡结果的74.7%在HemoCue读数的1.0g/dl范围内，23%在2.0g/dl范围内。
血红蛋白比色卡可以提高检测贫血的能力，特别是在资源匮乏国家无法使用HemoCue检测法的情况下。然而，每一例贫血病例都需要进一步调查以确定潜在病因。
