Chair of Evidence-Based Healthcare and Knowledge Translation, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Biomed Res Int. 2019 Jul 1;2019:2957429. doi: 10.1155/2019/2957429. eCollection 2019.
This papers aims to investigate the association between different levels of postpartum weight retention (PPWR) and cardiometabolic risk among the Saudi women 12 months postpartum.
This study is a follow-up of subgroup of cohort from Riyadh mother and baby multicenter cohort study. Clinical data were collected from participants 12 months after delivery and included current Body Mass Index (BMI), waist circumference, hip circumference, and blood pressure. In addition the following blood tests done were fasting blood glucose (FBG), glycosylated haemoglobin (HbA1c) levels, and lipids profile to assess the participants' cardiometabolic risks. The participants were categorized into three groups based on the level of PPWR: weight retention < 3kg; weight retention 3 to < 7kg; and weight retention ≥ 7kg. Subsequently, the prevalence of cardiometabolic risk factors was compared in the three groups to assess the association between different levels of PPWR and cardiometabolic risk factors. Logistic regression was used to test the effect of PPWR in the development of metabolic syndrome and Adjusted Odds Ratio (AOR) was calculated.
A total of 115 women participated in this study. Around 35% of the study population retained ≥ 7 kg of weight. The prevalence of cardiometabolic risk factors, including metabolic syndrome (MetS), increases with the increase of PPWR (p<0.01). The prevalence of MetS is 13% with highest frequency in the group with the highest weight retention. The determinants developing MetS were prepregnancy weight; AOR (95% CI); 1.08 (1.02-1.14), P< 0.01, current BMI, AOR (95% CI); 1.30 (1.12-1.51), P< 0.01, and FBG during pregnancy, AOR (95% CI); and 4.82 (1.72-13.48), P < 0.01.
Increased weight retention after delivery augments the rate of occurrence of cardiometabolic risk factors. Determinants of the development of MetS in postpartum Saudi women are increased prepregnancy weight, current BMI, and FBG during pregnancy.
本研究旨在探讨沙特女性产后 12 个月时不同程度的产后体重滞留（PPWR）与心血管代谢风险之间的关系。
本研究是利雅得母婴多中心队列研究的亚组随访。临床数据于产后 12 个月从参与者处收集，包括当前体重指数（BMI）、腰围、臀围和血压。此外，还进行了以下血液检查，以评估参与者的心血管代谢风险：空腹血糖（FBG）、糖化血红蛋白（HbA1c）水平和血脂谱。根据 PPWR 水平将参与者分为三组：体重滞留<3kg；体重滞留 3 至<7kg；体重滞留≥7kg。随后，比较三组中心血管代谢危险因素的患病率，以评估不同程度的 PPWR 与心血管代谢危险因素之间的关系。采用逻辑回归检验 PPWR 对代谢综合征发展的影响，并计算调整后的优势比（AOR）。
共有 115 名女性参与了这项研究。约 35%的研究人群体重滞留≥7kg。随着 PPWR 的增加，心血管代谢危险因素的患病率（包括代谢综合征（MetS））也随之增加（p<0.01）。MetS 的患病率为 13%，体重滞留最高的组患病率最高。发生 MetS 的决定因素是孕前体重；AOR（95%CI）；1.08（1.02-1.14），P<0.01，当前 BMI，AOR（95%CI）；1.30（1.12-1.51），P<0.01，以及怀孕期间的 FBG，AOR（95%CI）；和 4.82（1.72-13.48），P<0.01。
产后体重滞留增加会增加心血管代谢危险因素的发生几率。产后沙特女性发生 MetS 的决定因素是孕前体重增加、当前 BMI 和怀孕期间的 FBG。
