Szabad J, Erdélyi M, Szidonya J
Institute of Genetics, Biological Research Center of the Hungarian Academy of Sciences, Szeged.
Acta Biol Hung. 1987;38(2):257-66.
Fs(2)1 is a germ-line dependent dominant female sterile mutation of Drosophila melanogaster. Fs(2)1 heterozygous females deposit very few abnormal eggs (collapsed, with malformed chorion). The degeneration of egg primorida starts around the end of egg maturation. Mitotic recombination mapping locates Fs(2)1 in a distal region of the left arm of the 2nd chromosome. Fs(2)1 is a good tool for studying germ-line functions (by the dominant female sterile technique) because the frequency of germ-line mosaicism exceeds 20% upon irradiation of adult females. Salivary gland polytene chromosomes of Fs(2)1 and the revertant heterozygous larvae appear normal.
Fs(2)1是果蝇的一种种系依赖性显性雌性不育突变。Fs(2)1杂合子雌性产下的异常卵（塌陷、卵壳畸形）极少。卵原基的退化在卵成熟末期左右开始。有丝分裂重组定位将Fs(2)1定位于第二染色体左臂的远端区域。Fs(2)1是研究种系功能（通过显性雌性不育技术）的良好工具，因为成年雌性受辐射后种系嵌合体的频率超过20%。Fs(2)1和回复体杂合幼虫的唾液腺多线染色体看起来正常。
