Hoffman W H, Steinhart C M, el Gammal T, Steele S, Cuadrado A R, Morse P K
Department of Pediatrics, Medical College of Georgia, Augusta 30912.
AJNR Am J Neuroradiol. 1988 Jul-Aug;9(4):733-9.
To determine the effects of diabetic ketoacidosis on the brain, we studied nine consecutive patients between the ages of 6 and 17 years by performing cranial CT on three occasions: on admission, before treatment; 6-8 hr after beginning treatment; and 7 days after admission. Both the pretreatment scans and those at 6-8 hr showed significantly reduced size of the lateral and third ventricles in comparison with the 7-day scans. A comparison of the pretreatment scans with those done at 6-8 hr showed no statistically significant differences. We conclude that the cerebral swelling of diabetic ketoacidosis is usually present before treatment.
为了确定糖尿病酮症酸中毒对大脑的影响，我们对9名年龄在6至17岁之间的连续患者进行了研究，在三个时间点进行头颅CT检查：入院时，即治疗前；开始治疗后6 - 8小时；入院后7天。与7天的扫描结果相比，治疗前的扫描以及6 - 8小时的扫描均显示侧脑室和第三脑室的大小显著减小。治疗前的扫描与6 - 8小时的扫描结果比较，无统计学显著差异。我们得出结论，糖尿病酮症酸中毒引起的脑肿胀通常在治疗前就已存在。
