Yang Shih-Chieh, Chiu Yen-Chun, Chen Hung-Shu, Kao Yu-Hsien, Jou I-Ming, Tu Yuan-Kun
Department of Orthopedic Surgery, E-Da Hospital, I-Shou University, Kaohsiung.
J Orthop Surg (Hong Kong). 2019 Sep-Dec;27(3):2309499019863356. doi: 10.1177/2309499019863356.
The purpose of this study is to evaluate the efficacy of percutaneous endoscopic debridement and drainage (PEDD) in patients with surgical site infection (SSI) following instrumented lumbar fusion.
We retrospectively reviewed the medical records of 20 patients (6 women and 14 men; average age, 60.1 years) who underwent PEDD at our institute to treat SSI following instrumented lumbar fusion from January 2010 to December 2015. The terminal event, or failure of PEDD treatment, was defined as a shift in treatment methods to open surgery. Risk factors were analyzed to determine their effect on the therapeutic results of PEDD. Clinical outcomes were assessed by careful physical examination, regular serologic testing, and imaging studies to determine whether continued conservative treatment or open surgery was necessary.
Causative bacteria was identified in 17 (85%) of the 20 biopsy specimens. Successful infection control through PEDD was identified in 13 patients (65%). Both the visual analog scale and Oswestry disability index significantly improved in these patients. Detection of the causative pathogens was the only risk factor influencing the terminal event in the remaining seven patients (35%).
In this study, PEDD was an effective treatment approach for obtaining a bacteriological diagnosis, relieving the patient's symptoms, and assisting in eradication of SSI following instrumented lumbar fusion. The use of species-specific antibiotics for the offending pathogens appears to be the most important factor to determine the success rate. The indications of this procedure could be extended to treat patients with SSI after instrumented lumbar fusion.
本研究旨在评估经皮内镜清创引流术(PEDD)在器械辅助下腰椎融合术后手术部位感染(SSI)患者中的疗效。
我们回顾性分析了2010年1月至2015年12月期间在我院接受PEDD治疗器械辅助下腰椎融合术后SSI的20例患者(6例女性,14例男性;平均年龄60.1岁)的病历。PEDD治疗的终末事件或失败定义为治疗方法转为开放手术。分析危险因素以确定其对PEDD治疗结果的影响。通过仔细的体格检查、定期的血清学检测和影像学研究评估临床结果,以确定是否需要继续保守治疗或开放手术。
20份活检标本中有17份(85%)鉴定出病原菌。13例患者(65%)通过PEDD成功控制了感染。这些患者的视觉模拟评分和Oswestry功能障碍指数均显著改善。在其余7例患者(35%)中,检测到病原菌是影响终末事件的唯一危险因素。
在本研究中,PEDD是一种有效的治疗方法,可用于获得细菌学诊断、缓解患者症状并协助根除器械辅助下腰椎融合术后的SSI。使用针对致病病原体的特异性抗生素似乎是决定成功率的最重要因素。该手术的适应证可扩展至治疗器械辅助下腰椎融合术后的SSI患者。