Ogun Gabriel Olabiyi, Okoro Obumneme Emeka
Department of Pathology, University of Ibadan/ University College Hospital, Ibadan, Nigeria.
Dermatology unit, Department of Medicine, University of Ibadan/ University College Hospital, Ibadan, Nigeria.
Pan Afr Med J. 2016 Apr 22;23:221. doi: 10.11604/pamj.2016.23.221.9372. eCollection 2016.
Non-neoplastic skin lesions constitute the majority of skin diseases. There is a paucity of histopathology studies of non-neoplastic skin diseases in Nigeria and the West Africa sub-region in general. This is because the dermato-pathology sub-specialty is poorly developed. Therefore, the main aim of this study is to determine the spectrum of histologically diagnosed non-neoplastic skin lesions in Ibadan, Nigeria.
This is a retrospective study. All non-neoplastic skin lesions diagnosed in the Department of Pathology, University College Hospital, Ibadan over a five year period. (January 2006 to December 2010) was reviewed. The lesions were classified into eight groups according to the International Classification of Diseases (ICD)-10 of skin and subcutaneous disorders. The main classes include Dermatitis/Eczema, Papulosquamous disorders, Infectious disorders, Connective tissue diseases, Bullous disorders, Naevi/Developmental lesions, Granulomatous lesions, keratinizing disorders and other categories/Miscellaneous group.
A total of 209 non-neoplastic skin lesions comprised 1.3% of all surgical pathology specimen received within the study period. The modal age group was 20-29. The Dermatitis/Eczema group has the highest frequency of 87 cases representing 41.6% of cases, papulosquamous disorders 39 (18.7%), infectious disorders 37 (17.7%), bullous disorders 11 (5.3%) and connective tissue disorder 9 (4.3%). Chronic non-specific dermatitis was the commonest specific diagnosis comprising 60 cases (28.7%) of all the skin diseases. The other common specific skin lesions were lichen planus/lichenoid dermatitis 27(12.9% of 209 cases), verruca vulgaris 25 (12% of 209 cases).
The number of histologically diagnosed non-neoplastic skin lesions is relatively small. There is a very wide spectrum of non-neoplastic skin lesions diagnosed within this period. There is a need for a specific diagnosis considering the high frequency of chronic non-specific dermatitis.
非肿瘤性皮肤病变构成了大多数皮肤病。在尼日利亚及整个西非次区域，对非肿瘤性皮肤病的组织病理学研究匮乏。这是因为皮肤病理学亚专业发展不完善。因此，本研究的主要目的是确定在尼日利亚伊巴丹经组织学诊断的非肿瘤性皮肤病变谱。
这是一项回顾性研究。对伊巴丹大学学院医院病理科在五年期间（2006年1月至2010年12月）诊断的所有非肿瘤性皮肤病变进行了回顾。根据皮肤和皮下疾病的国际疾病分类（ICD）-10，将病变分为八组。主要类别包括皮炎/湿疹、丘疹鳞屑性疾病、感染性疾病、结缔组织病、大疱性疾病、痣/发育性病变、肉芽肿性病变、角化性疾病以及其他类别/杂项组。
共有209例非肿瘤性皮肤病变，占研究期间接收的所有外科病理标本的1.3%。发病年龄组的众数为20 - 29岁。皮炎/湿疹组的发病率最高，为87例，占病例的41.6%，丘疹鳞屑性疾病39例（18.7%），感染性疾病37例（17.7%），大疱性疾病11例（5.3%），结缔组织病9例（4.3%）。慢性非特异性皮炎是最常见的具体诊断，占所有皮肤病的60例（28.7%）。其他常见的具体皮肤病变为扁平苔藓/苔藓样皮炎27例（占209例的12.9%），寻常疣25例（占209例的12%）。
经组织学诊断的非肿瘤性皮肤病变数量相对较少。在此期间诊断出的非肿瘤性皮肤病变谱非常广泛。鉴于慢性非特异性皮炎的高发病率，需要进行具体诊断。
