• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

抽脂术后心脏骤停:一例利多卡因毒性反应病例报告

Cardiac Arrest Following Liposuction: A Case Report of Lidocaine Toxicity.

作者信息

Mrad Sandra, El Tawil Chady, Sukaiti Waleed A, Bou Chebl Ralph, Abou Dagher Gilbert, Kazzi Ziad

机构信息

Emergency Department, American University of Beirut Medical Center, Beirut, Lebanon.

Department of Emergency Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Oman Med J. 2019 Jul;34(4):341-344. doi: 10.5001/omj.2019.66.

DOI:10.5001/omj.2019.66
PMID:31360324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6642719/
Abstract

We report a case of a patient presenting to the emergency department in cardiac arrest following a liposuction procedure, which was performed in a physician office using lidocaine anesthesia. During liposuction of the thighs, using the power-assisted technique, the patient was given a subcutaneous dose of lidocaine equal to 71 mg/kg without any noticeable intraoperative complication. Two hours later, the patient experienced dizziness, a rapid decline in mental status, tonic-clonic seizure, and cardiac arrest. The patient was successfully resuscitated in the emergency department with the return of spontaneous circulation after 22 minutes of continuous advanced cardiovascular life support resuscitation. The patient suffered from subsequent severe hypoxic-ischemic brain injury, and a complicated hospital stay, including brain edema, electrolytes disturbances, and nosocomial infections contributed to her death two months later due to septic shock.

摘要

我们报告了一例患者,该患者在抽脂手术后心脏骤停被送至急诊科。抽脂手术是在医生办公室使用利多卡因麻醉进行的。在使用动力辅助技术进行大腿抽脂过程中,患者接受了皮下注射剂量为71mg/kg的利多卡因,术中未出现任何明显并发症。两小时后,患者出现头晕、精神状态迅速下降、强直阵挛性癫痫发作及心脏骤停。在急诊科经过22分钟持续的高级心血管生命支持复苏后,患者成功恢复自主循环。患者随后遭受了严重的缺氧缺血性脑损伤,住院期间病情复杂,包括脑水肿、电解质紊乱和医院感染,两个月后因感染性休克死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b18/6642719/dbff73813ca0/OMJ-D-18-00023-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b18/6642719/dbff73813ca0/OMJ-D-18-00023-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b18/6642719/dbff73813ca0/OMJ-D-18-00023-f1.jpg

相似文献

1
Cardiac Arrest Following Liposuction: A Case Report of Lidocaine Toxicity.抽脂术后心脏骤停:一例利多卡因毒性反应病例报告
Oman Med J. 2019 Jul;34(4):341-344. doi: 10.5001/omj.2019.66.
2
Lidocaine-Induced Cardiac Arrest in the Emergency Department: Effectiveness of Lipid Therapy.急诊科利多卡因诱发的心脏骤停:脂质治疗的有效性
J Emerg Med. 2016 Jan;50(1):47-50. doi: 10.1016/j.jemermed.2015.07.035. Epub 2015 Oct 23.
3
Tumescent liposuction: standard guidelines of care.肿胀吸脂术:护理标准指南
Indian J Dermatol Venereol Leprol. 2008 Jan;74 Suppl:S54-60.
4
Reporting a fatality during tumescent liposuction.肿胀吸脂术中死亡病例报告。
Forensic Sci Int. 2008 Jun 10;178(1):e11-6. doi: 10.1016/j.forsciint.2008.01.013. Epub 2008 Mar 14.
5
Safe extensive tumescent liposuction with segmental infiltration of lower concentration lidocaine under monitored anesthesia care.在麻醉监护下采用低浓度利多卡因分段浸润进行安全的大面积肿胀吸脂术。
Ann Plast Surg. 2015 Jan;74(1):6-11. doi: 10.1097/SAP.0b013e3182933de7.
6
2005 American Heart Association (AHA) guidelines for cardiopulmonary resuscitation (CPR) and emergency cardiovascular care (ECC) of pediatric and neonatal patients: pediatric basic life support.2005年美国心脏协会(AHA)关于儿科和新生儿患者心肺复苏(CPR)及紧急心血管护理(ECC)的指南:儿科基础生命支持
Pediatrics. 2006 May;117(5):e989-1004. doi: 10.1542/peds.2006-0219.
7
Atlanto-occipital dislocation in a patient presenting with out-of-hospital cardiac arrest: a case report and literature review.一名院外心脏骤停患者的寰枕关节脱位:病例报告及文献综述
J Med Case Rep. 2019 Feb 26;13(1):44. doi: 10.1186/s13256-018-1926-2.
8
2018 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.2018 年美国心脏协会儿童高级生命支持重点更新:对美国心脏协会心肺复苏和紧急心血管护理指南的更新。
Circulation. 2018 Dec 4;138(23):e731-e739. doi: 10.1161/CIR.0000000000000612.
9
Tumescent anesthesia with a lidocaine dose of 55 mg/kg is safe for liposuction.利多卡因剂量为55毫克/千克的肿胀麻醉用于吸脂手术是安全的。
Dermatol Surg. 1996 Nov;22(11):921-7. doi: 10.1111/j.1524-4725.1996.tb00634.x.
10
Estimated Maximal Safe Dosages of Tumescent Lidocaine.肿胀液利多卡因的估计最大安全剂量
Anesth Analg. 2016 May;122(5):1350-9. doi: 10.1213/ANE.0000000000001119.

引用本文的文献

1
Cerium-doped calcium carbonate microparticles combined with low-intensity ultrasound for efficient sonodynamic therapy in body sculpting.铈掺杂碳酸钙微粒联合低强度超声用于身体塑形中的高效声动力治疗
J Biol Eng. 2025 Apr 28;19(1):39. doi: 10.1186/s13036-025-00505-z.
2
Seizure following in-office lidocaine administration: a case report on local anesthetic systemic toxicity.门诊利多卡因注射后癫痫发作:一例局部麻醉药全身毒性病例报告
Ther Adv Drug Saf. 2025 Mar 17;16:20420986251318843. doi: 10.1177/20420986251318843. eCollection 2025.
3
Lipid emulsion for xenobiotic overdose: PRO.

本文引用的文献

1
Tumescent anaesthesia: its applications and well tolerated use in the out-of-operating room setting.肿胀麻醉:其在非手术室环境中的应用及良好耐受性使用。
Curr Opin Anaesthesiol. 2017 Aug;30(4):518-524. doi: 10.1097/ACO.0000000000000486.
2
Local Anesthetic Systemic Toxicity and Liposuction: Looking Back, Looking Forward.局部麻醉药全身毒性与抽脂术:回顾与展望
Anesth Analg. 2016 May;122(5):1250-2. doi: 10.1213/ANE.0000000000001247.
3
Estimated Maximal Safe Dosages of Tumescent Lidocaine.肿胀液利多卡因的估计最大安全剂量
脂肪乳剂治疗外源性药物中毒:支持。
Br J Clin Pharmacol. 2023 Jun;89(6):1708-1718. doi: 10.1111/bcp.15620. Epub 2023 Apr 4.
4
Sudden Cardiac Arrest During a Prolonged Liposuction and Lipofilling Procedure: A Case Report.一例长时间抽脂及脂肪填充手术过程中发生心脏骤停的病例报告
Cureus. 2022 Jun 16;14(6):e25985. doi: 10.7759/cureus.25985. eCollection 2022 Jun.
5
An unusual case of oral surgical management in a patient with isovaleric acidemia and schizophrenia: A case report.一例异戊酸血症合并精神分裂症患者的口腔外科治疗特殊病例:病例报告
Biomed Rep. 2022 Jun 7;17(2):64. doi: 10.3892/br.2022.1547. eCollection 2022 Aug.
6
Severe Postoperative Bleeding Following Minor-to-Moderate Abdominal and Flank Liposuction Performed at a Day Surgery Center: A Case Report.在日间手术中心行小-中度腹部和侧腹脂肪抽吸术后严重术后出血:一例报告。
Am J Case Rep. 2022 Feb 5;23:e934049. doi: 10.12659/AJCR.934049.
7
The Synthesis of Europium-Doped Calcium Carbonate by an Eco-Method as Free Radical Generator Under Low-Intensity Ultrasonic Irradiation for Body Sculpture.通过生态方法在低强度超声辐照下合成掺铕碳酸钙作为用于身体塑形的自由基发生器
Front Bioeng Biotechnol. 2021 Nov 19;9:765630. doi: 10.3389/fbioe.2021.765630. eCollection 2021.
Anesth Analg. 2016 May;122(5):1350-9. doi: 10.1213/ANE.0000000000001119.
4
Intractable cardiac arrest due to lidocaine toxicity successfully resuscitated with lipid emulsion.脂肪乳剂成功救治难治性利多卡因中毒性心搏骤停
Crit Care Med. 2011 Apr;39(4):872-4. doi: 10.1097/CCM.0b013e318208eddf.
5
ASRA practice advisory on local anesthetic systemic toxicity.全身麻醉中毒的 ASRA 实践指南
Reg Anesth Pain Med. 2010 Mar-Apr;35(2):152-61. doi: 10.1097/AAP.0b013e3181d22fcd.
6
Major and lethal complications of liposuction: a review of 72 cases in Germany between 1998 and 2002.抽脂术的主要及致命并发症:对1998年至2002年间德国72例病例的回顾
Plast Reconstr Surg. 2008 Jun;121(6):396e-403e. doi: 10.1097/PRS.0b013e318170817a.
7
Office surgery incidents: what seven years of Florida data show us.门诊手术事故:佛罗里达州七年数据带给我们的启示
Dermatol Surg. 2008 Mar;34(3):285-91; discussion 291-2. doi: 10.1111/j.1524-4725.2007.34060.x. Epub 2007 Dec 20.
8
Maximum recommended doses of local anesthetics: a multifactorial concept.局部麻醉药的最大推荐剂量:一个多因素概念。
Reg Anesth Pain Med. 2004 Nov-Dec;29(6):564-75; discussion 524. doi: 10.1016/j.rapm.2004.08.003.
9
Guidelines of care for liposuction.
J Am Acad Dermatol. 2001 Sep;45(3):438-47. doi: 10.1067/mjd.2001.117045.
10
Fatal outcomes from liposuction: census survey of cosmetic surgeons.抽脂术导致的致命后果:整形外科医生的普查
Plast Reconstr Surg. 2000 Jan;105(1):436-46; discussion 447-8. doi: 10.1097/00006534-200001000-00070.